Today, remyelination holds real promise as a strategy for restoring lost function and slowing or even stopping MS progression. This week, we're taking a deep dive into the current state of remyelination research. Joining me are Dr. Jeffrey Cohen, the Hazel Prior Hostetler Professor of Neurology at the Cleveland Clinic and the director of the Cleveland Clinic's Mellen Center for Multiple Sclerosis Treatment and Research, and Dr. Ian Duncan, a neuroscientist, and Professor of Neurology at the University of Wisconsin-Madison and the recipient of the 2020 Dystel Prize for MS Research.
“Although our method of diagnosis is not considered a gold standard, it likely represents the closest, most practical way that we have at the moment to characterize consequential lung disease in dairy calves,” said lead author Dr. Theresa Ollivett with the department of medical sciences in the University of Wisconsin-Madison School of Veterinary Medicine.
Last week, after a series of experiments in cells and hamsters, he and Yoshihiro Kawaoka at the University of Wisconsin published a more complete case in Science. The implications for the history of the virus and its likely future are profound.
“We saw that the mutant virus transmits better airborne than the [original] virus, which may explain why this virus dominated in humans,” said Yoshihiro Kawaoka, a virologist at the University of Wisconsin who collaborated with the UNC team.
Pan Genome Systems, another Madison company working on a vaccine for COVID-19, found in a study — which is currently under review — that its vaccine could work in mice, said founder Adel Talaat. Pan Genome is now working to secure more funding to test the vaccine in more animal subjects before moving to human trials.
Gary Oetzel, D.V.M., a professor for the University of Wisconsin-Madison’s School of Veterinary Medicine, shared that detail and more during the September Hoard’s Dairyman monthly webinar. He started out by defining the two types of hypocalcemia: clinical and subclinical.
Also providing input are experts in calf health and bovine veterinary medicine: Theresa Ollivett, DVM, PhD and Courtney Halbach, MBA, of the Department of Medical Sciences in the UW-Madison School of Veterinary Medicine; and Sandy Stuttgen, DVM, of UW-Madison Extension in Taylor County. As well, Tina Kohlman, MS, of UW-Madison Extension in Fond du Lac County, contributed expertise in dairy calf and heifer management.
That was backed by genetic sequencing of COVID-19 cases in the two counties. Only 75 miles apart, there was little transmission of the disease between Madison and Milwaukee. Those findings come in a new study authored by Thomas Friedrich, a professor in the UW School of Veterinary Medicine, and was published Thursday in the journal Nature Communications. By comparing different strains of the virus, researchers can tell where it’s spreading.
Tony Goldberg, a veterinarian at the University of Wisconsin, Madison, and the head of the Kibale EcoHealth Project, said that he has seen the devastation wrought by respiratory diseases among chimpanzees. A deadly outbreak in 2013 at the reserve turned out to be the result of human rhinovirus C, the most common cause of the common cold worldwide. Until then, it had never been seen in chimps.