Education

• Clinical Professor of Comparative Ophthalmology

• BS 1982, Michigan State University
• DVM 1983, Michigan State University
• Diplomate, American College of Veterinary Ophthalmologists

Research

Dr. Miller's principal research interests are the regulation of intraocular pressure in both health and glaucoma and comparative ocular pharmacology.  His primary research emphasis has been to standardize methods of determining intraocular pressure (tonometry) and to elucidate the mechanisms by which glaucoma occurs in the dog, specifically as to why the drainage closes in canine primary angle-closure glaucoma. Additionally, he has an interest in clinically applicable methods of maintaining vision in dogs with glaucoma. He has also worked extensively in the area of comparative ocular pharmacology.

Responsibilities

Comparative ophthalmology in the third year of the professional curriculum and the clinical rotation in Comparative Ophthalmology for senior students; continuing education for private practitioners and resident-level training. Dr. Miller also has edited Slatter's Fundamentals of Veterinary Ophthalmology, the ophthalmology section fo the Five Minute Veterinary Consult and has authored over 40 book chapters, approximately 50 formal scientific manuscripts and has given over 300 formal presentations at national and international meetings.

Clinical Interests

Comparative ophthalmology with a special emphais on glaucoma and ocular pharmacology

Recent Publications

Textbooks Authored

1. Miller PE, Tilley LP, Smith FWK (eds). Ophthalmology: The Five-Minute Veterinary Consult Canine and Feline Speciality Handbook. Lippincott Williams & Wilkins; Baltimore MD 2006; 306 pages. ISBN 0-7817-7063-7. Also translated into Japanese.

2. Maggs DJ, Miller PE, Ofri R. Slatter’s Fundamentals of Veterinary Ophthalmology, Fourth edition. Saunders Elsevier: St Louis. Mo. 2008. 475 pages. ISBN: 978-7216-0561-6. Also translated into Portuguese and Korean. Fifth Edition is in press.

Editorial Roles

1. Section Editor: Ophthalmology. In Tilley LP, Smith FWK (eds): The Five Minute Veterinary Consult: Canine and Feline, First through Fourth Editions. Baltimore, Maryland, Williams and Wilkins Co. 1997 to date.

2. Editorial Board: Veterinary Ophthalmology. Blackwell Publishing. 2005 to date.

3. Special Edition Editor: Glaucoma. Veterinary Ophthalmology. 2007; 10 (Supplement 1):1-124.

Select Book Chapters

1. Miller PE. Glaucoma. In: Bonagura JD and Kirk RW (eds). Current Veterinary Therapy XII: Small Animal Practice. Philadelphia, Pennsylvania, WB Saunders Co. 1995;1265-1272.

2. Miller PE. Exotic Small Mammal Ophthalmic Cases. In: Brown SA, Rosenthal K (eds). Self assessment color review of small mammals. London, England, Manson Publishing Ltd. 1997.

3. Miller PE. Ferret Ophthalmology. Seminars in Avian and Exotic Pet Medicine. WB Saunders Co, Philadelphia. 1997;6:146-151.

4. Slatter D, Miller PE. Structure and Function of the Eye. In: Slatter D (ed). Fundamentals of Veterinary Ophthalmology, 3rd Edition. Philadelphia: WB Saunders Co. 2001:1-20.

5. Miller PE. Glaucoma. In: Slatter D (ed). Textbook of Small Animal Surgery, 3rd Edition. WB Saunders Co. 2003:1454-1477.

6. Miller PE. Equine Vision and Optics. In: Robinson NE (ed). Current Therapy in Equine Medicine 5th edition. St. Louis: Saunders 2003:454-457.

7. Miller PE, Dubielzig RR. Ocular tumors. In: Withrow SJ and Vail DM (eds). Clinical Veterinary Oncology, Fourth Edition. Saint Louis, Missouri, Saunders Elsevier. 2007:686-698.

8. Miller PE. Neurogenic Vision Loss. Current Veterinary Therapy, 5th Edition - Food Animal Practice. Anderson De, Rings M (eds). Philadelphia, WB Saunders Co. 2009.

9. Miller PE. Feline Glaucoma. In: Bonagura JD and Kirk RW (eds). Kirk’s Current Veterinary Therapy XIV: Small Animal Practice. Philadelphia, Pennsylvania, WB Saunders Co. 2009.

10. Miller PE. Corneal and Scleral lacerations. In: Tilley LP, Smith FWK (eds). Blackwell’s Five Minute Veterinary Consult: Canine and Feline. Fifth Edition. Hoboken, New Jersey. Wiley-Blackwell. 2011.

11. Miller PE. Blind Quiet Eye. In: Tilley LP, Smith FWK (eds). Blackwell’s Five Minute Veterinary Consult: Canine and Feline. Fifth Edition. Hoboken, New Jersey. Wiley-Blackwell. 2011.

12. Miller PE. Red Eye. In: Tilley LP, Smith FWK (eds). Blackwell’s Five Minute Veterinary Consult: Canine and Feline. Fifth Edition. Hoboken, New Jersey. Wiley-Blackwell. 2011.

13. Miller PE. Episcleritis. In: Tilley LP, Smith FWK (eds). Blackwell’s Five Minute Veterinary Consult: Canine and Feline. Fifth Edition. Hoboken, New Jersey. Wiley-Blackwell. 2011.

14. Miller PE, Murphy CJ. Equine Vision: Normal and Abnormal. In Gilger BC (ed) Equine Ophthalmology 2nd edition. St Louis, Missouri Elsevier Saunders 397-433, 2011.

15. Miller PE, Dubielzig RR. Ocular tumors. In: Withrow SJ and Vail DM (eds). Clinical Veterinary Oncology, Fifth Edition. Saint Louis, Missouri, Saunders Elsevier. In Press.

16. Miller PE. Structure and Function of the Eye. In: Maggs DJ, Miller PE, Ofri R; Slatter’s Fundamentals of Veterinary Ophthalmology, 5th Edition. Saunders Elsevier St Louis, MO In Press.

17. Miller PE. Ocular Emergencies. In: Maggs DJ, Miller PE, Ofri R; Slatter’s Fundamentals of Veterinary Ophthalmology, 5th Edition. Saunders Elsevier St Louis, MO In Press.

18. Miller PE. The Glaucomas. In: Maggs DJ, Miller PE, Ofri R; Slatter’s Fundamentals of Veterinary Ophthalmology, 5th Edition. Saunders Elsevier St Louis, MO In Press.

19. Miller PE. Orbit. In: Maggs DJ, Miller PE, Ofri R; Slatter’s Fundamentals of Veterinary Ophthalmology, 4th Edition. Saunders Elsevier St Louis, MO 2007:352-373.

20. Miller PE. Uvea. In: Maggs DJ, Miller PE, Ofri R; Slatter’s Fundamentals of Veterinary Ophthalmology, 5th Edition. Saunders Elsevier St Louis, MO In Press.

21. Miller PE. Lacrimal System. In: Maggs DJ, Miller PE, Ofri R; Slatter’s Fundamentals of Veterinary Ophthalmology, 5th Edition. Saunders Elsevier St Louis, MO In Press.

22. Miller PE. Breed Predisposition to Eye Disorders. In: Maggs DJ, Miller PE, Ofri R; Slatter’s Fundamentals of Veterinary Ophthalmology, 5th Edition. Saunders Elsevier St Louis, MO In Press.

Select Scientific Papers

1. Miller PE, Pickett JP, Majors LJ. Evaluation of two applanation tonometers in horses. Am J Vet Res 1990;51:935 937.

2. Miller PE, Pickett JP, Majors LJ, Kurzman ID. Evaluation of two applanation tonometers in cats. Am J Vet Res 1991;52:1917-1921.

3. Miller PE, Pickett JP, Majors LJ, Kurzman ID. Clinical comparison of the Mackay Marg and Tono Pen applanation tonometers in the dog. Prog Vet & Compar Ophthalmol 1991;1:171-176.

4. Miller PE, Pickett JP, Comparison of the human and canine Schiotz tonometry conversion tables in clinically normal dogs. J Am Vet Med Assoc 1992;201:1021-1025.

5. Miller PE, Picket JP, Comparison of the human and canine Schiotz tonometry conversion tables in clinically normal cats. J Am Vet Med Assoc 1992;201:1017-1020.

6. Frischmeyer KJ, Miller PE, Bellay Y, Smedes SL, Brunson DB. Parenteral anticholinergics in dogs with normal and elevated intraocular pressure. Vet Surg 1993;22:230-234.

7. Miller PE, Marlar AB, Dubielzig RR. Cataracts in a laboratory colony of ferrets (Mustela putorius furo). Lab Anim Sci 1993;43:562 568.

8. Miller PE, Panciera DL. Effects of experimentally induced hypothyroidism on the eye and ocular adnexa of dogs. Am J Vet Res 1994;55:692 697.

9. Miller PE, Langenberg JA, Baeten LA, Moore CP. Pseudomonas aeruginosa associated corneal ulcers in captive cranes. J Zoo Wildlife Med 1994;25:449 454.

10. Stanz KM, Miller PE, Cooley AJ, Langenberg JA, Murphy CJ. Mycobacterial keratitis in a parrot. J Am Vet Med Assoc 1995;206:1177-1180.

11. Miller PE, Murphy CJ. Intraocular pressure measurement through two types of plano therapeutic soft contact lenses in dogs. Am J Vet Res 1995;56:1418-1420.

12. Miller PE, Murphy CJ. Vision in dogs. J Am Vet Med Assoc 1995;207:1623-1634.

13. Miller PE, Langenberg JA, Hartmann FA. The normal aerobic bacterial conjunctival flora of three species of captive cranes. J Zoo Wildlife Med 1995;26:545-549.

14. Miller PE, Nelson MJ, Rhaesa SL. Effects of topical administration of 0.5% apraclonidine on intraocular pressure, pupil size and heart rate in normal dogs. Am J Vet Res 1996;57:79-82.

15. Miller PE, Rhaesa SL. Effects of topical administration of 0.5% apraclonidine on intraocular pressure, pupil size and heart rate in normal cats. Am J Vet Res 1996;57:83-86.

16. Miller PE, Stanz KM, Dubielzig RR, Murphy, CJ. Mechanisms of acute intraocular pressure increases after phacoemulsification. Am J Vet Research 1997;58:1159-1165.

17. Miller PE, Galbreath EJ, Kehren JC, Steinberg H, Dubielzig RR. Photoreceptor cell death by apoptosis in canine sudden acquired retinal degeneration syndrome. Am J Vet Res. 1998;59:149-152.

18. Stuhr CM, Miller PE, Murphy CJ, Schoster JV, Thomas CB. The effects of intracameral carbachol on post-operative intraocular pressure rises after cataract extraction in dogs. J Am Vet Med Assoc 1998;212:1885-1888.

19. Adams WM, Miller PE, Vail DM, Forrest LJ, MacEwen EG. An accelerated technique for irradiation of malignant canine nasal and paranasal sinus tumors. Veterinary Radiology & Ultrasound 1998;39:475-481.

20. Bentley E, Miller PE, Murphy CJ, Schoster JV. Combined cycloablation and gonioimplantation for treatment of glaucoma in dogs: 18 cases (1992-1998). J Am Vet Med Assoc 1999:215:1469-1472.

21. Massa KL, Murphy CJ, Miller PE, Korsower CS, Young KM. Usefulness of aerobic microbial culture and cytologic evaluation of corneal specimens in the diagnosis of infectious ulcerative keratitis in animals. J Am Vet Med Assoc 1999;215:1671-1674.

22. Miller PE, Schmidt GM, Vainisi SJ, Swanson JF, Herrmann MK. The efficacy of topical prophylactic antiglaucoma therapy in primary closed angle glaucoma in dogs: A multicenter clinical trial. Journal of the American Animal Hospital Association 2000;36:431-438.

23. Lannek EB, Miller PE, Development of glaucoma after phacoemulsification for removal of cataracts in dogs: 22 cases (1987-1997). J Am Vet Med Assoc, 2001;218:70-76.

24. Kroll MM, Miller PE, Rodan R. Intraocular pressure measurements obtained as part of a comprehensive geriatric health examination from cats seven years of age or older. J Am Vet Med Assoc, 2001; 219:1406-1410.

25. Whiteman AL, Klauss G, Miller PE, Nayden DK, Dubielzig RR. Morphologic features of degeneration and cell death in the neurosensory retina in primary angle-closure glaucoma in dogs. Am J Vet Res 2002; 63:257-261.

26. Bentley E, Diehl KA, Miller PE. Use of high-resolution ultrasound as a diagnostic tool in veterinary ophthalmology. J Am Vet Med Assoc 2003; 223:1617-1622.

27. Paglia, D, Miller PE, Dubielzig RR. James Wardrop and equine recurrent uveitis. Archives of Ophthalmology, 2004;122:1218-1223.

28. Smith LJ, Bentley E, Shih A, Miller PE. Systemic lidocaine infusion as an analgesic for intraocular surgery in dogs: A pilot study. Veterinary Anaesthesia and Analgesia 2004;31:53-63.

29. Knollinger AM, La Croix NC, Barrett P, Miller PE. An evaluation of a rebound tonometer for measuring intraocular pressure in dogs and horses. Journal of the American Veterinary Medical Association, 2005; 227:244-248.

30. Czederpiltz JMC, La Croix NC, van der Woerdt A, Bentley E, Dubielzig RR, Murphy CJ, Miller PE. Putative aqueous humor misdirection syndrome as a cause of glaucoma in cats: 32 cases. Journal of the American Veterinary Medical Association. 2005;227:1476-1479.

31. Bentley E, Diehl KA, Miller PE. Evaluation of intra- and interobserver reliability and image reproducibility to assess usefulness of high-resolution ultrasonography for measurement of anterior segment structures of canine eyes. American Journal of Veterinary Research, 2005; 66:1775-1779.

32. Pauli AM, Bentley E, Diehl KA, Miller PE. Effects of the Application of Neck Pressure by a Collar or Harness on Intraocular Pressure in Dogs. Journal of the American Animal Hospital Association, 2006, 42:207-211.

33. Miller PE. Veterinary Glaucoma Research. Veterinary Ophthalmology 2007 ; 10 (Supplement 1) :1-2.

34. Kubai MA, Bentley E, Miller PE, Mutti DO, Murphy CJ. Refractive state of eyes and association between ametropia and breed in dogs. American Journal of Veterinary Research 2008, 69:946-51.

35. Miller PE. Acute Primary Angle-Closure Glaucoma. Clinicians Brief 2008;6:25-28.

36. Miller PE. Exophthalmos. Clinicians Brief 2008:6:22-23.

37. Martin PL, Miller PE, Mata M, Christian B. Ocular inflammation in cynomolgus macaques following intravenous administration of a human monoclonal antibody. Journal of Toxicology 2009;28:5-16.

38. Myrna K, Pot S, Bentley E, Adkins E, Miller PE, Murphy CJ. Toxic Anterior Segment Syndrome: Are we missing it? Veterinary Ophthalmology 2009, 12(2)138.

39. Lawrence JA, Forrest LJ, Turek MM, Miller PE, Mackie TR, Juradat HA, Vail DM, Dubielzig RR, Chappell R, Mehta MP. Proof of principle of ocular sparing in dogs with sinonasal tumors treated with intensity-modulated radiation therapy. Vet Radiol Ultrasound, 2010:51:561-570

40. Smith LN, Miller PE. Effects of topical administration of latanoprost, timolol or a combination of latanoprost and timolol on intraocular pressure, pupil size, and heart rate in clinically normal dogs. American Journal of Veterinary Research 2010:71:1055-61. The abstract of this paper was reprinted in Journal of American Veterinary Medical Assoociation, 2010;237:554.

41. Murphy CJ, Bentley E, Miller PE, McIntyre K, Leatherberry G, Dubielzig D, Giuliano E, Moore CP, Phillips TE, Scagliotti R, Esson D, Gadek T, O’Neill C. The Pharmacological Assessment of a Novel Lymphocyte Function-Associated Antigen-1 Antagonist (SAR 1118) for the Treatment of Keratoconjunctivitis Sicca in Dogs. Accepted Investigative Ophthalmology and Visual Science. (e-pub ahead of print February 17, 2011 IOVS 09-5078).

42. Nork TM, Dubielzig RR, Christian BJ, Miller PE, Miller JM, Cao J, Zimmer EP, Wiegand SJ. VEGF Trap Prevents Experimental Choroidal Neovascularization and Causes Rapid Resolution of Active Lesions in Non-Human Primates. Archives of Ophthalmology, 2011; 129(8):1042-1052.

43. McLellan GJ, Miller PE. Feline Glaucoma – a comprehensive review. Vet Ophthalmol 2011 (Supplement 1);14:15-29.

44. Tsai S, Bentley E, Miller PE, Espinheira F, Vangyi C, Wiese A, Almazan A, Li H, Conforti P, Lee SS, Robinson MR. Gender Differences in Iridocorneal Angle Morphology in Dogs. Veterinary Ophthalmology 2012 (Supplement 1); 15:60-63. DOI:10.1111/j.1463-5224.2011.00956.x

45. Tsai S, Miller PE, Struble C, Howard S, Almazan A, Burke JA, Hughes PM, Li H, Conforti P, Lee SS, Robinson MR. Topical Application of 0.005% Latanoprost Increases Episcleral Venous Pressure in Normal Dogs. 2011, Veterinary Ophthalmology 2012 (Supplement 1); 15:60-63. DOI:10.1111/j.1463-5224.2011.00970.x

46. Nork TM, Murphy CJ, Kim CBY, Ver Hoeve JN, Rasmussen CA, Miller PE, Wabers HD, Neider MW, Dubielzig RR, McCulloh RJ, Christian BJ. Functional and Anatomic Consequences of Subretinal Dosing in the Cynomolgus Macaque. Archives of Ophthalmology, 2012; 130(1):65-75 (Epub ahead of print 2011 Sep 12).