Suzuki Lab


Articles (71 total):

Tey SR, Mueller M, Reilly M, Switalski C, Robertson S, Sakanaka-Yokoyama M, Suzuki M (2022). Cell Surface Proteins for Enrichment and In Vitro Characterization of Human Pluripotent Stem Cell-Derived Myogenic Progenitors. Stem Cells Int2022;2022:2735414. PubMed Central PMCID: PMC8894063.

Lynch E, Peek E, Reilly M, FitzGibbons C, Robertson S, Suzuki M (2022).
Current Progress in the Creation, Characterization, and Application of Human Stem Cell-derived in Vitro Neuromuscular Junction Models. Stem Cell Rev Rep2022 Feb;18(2):768-780.  PubMed Central PMCID: PMC8720113.

Lynch EM, Robertson S, FitzGibbons C, Reilly M, Switalski C, Eckardt A, Tey SR, Hayakawa K, Suzuki M (2021). Transcriptome analysis using patient iPSC-derived skeletal myocytes: Bet1L as a new molecule possibly linked to neuromuscular junction degeneration in ALS. Exp Neurol.  Nov;345:113815. PubMed Central PMCID: PMC8429236.

Reiss J, Robertson S, Suzuki M (2021). Cell Sources for Cultivated Meat: Applications and Considerations throughout the Production Workflow. Int J Mol Sci. Jul 13;22(14).  PubMed Central PMCID: PMC8307620.

Lynch E, Peek E, Reilly M, FitzGibbons C, Robertson S, Suzuki M (2021). Current Progress in the Creation, Characterization, and Application of Human Stem Cell-derived in Vitro Neuromuscular Junction Models. Stem Cell Rev Rep. Jul 1. PubMed PMID: 34212303.

Kletzien H, Kelm-Nelson CA, Wang S, Suzuki M, Connor NP (2020). Myogenic marker expression as a function of age and exercise-based therapy in the tongue. Exp Gerontol. Dec;142:111104.  PubMed Central PMCID: PMC7748063.

Tey, S-R, Robertson S, Lynch E, Suzuki M (2019). Coding Cell Identity of Human Skeletal Muscle Progenitor Cells Using Cell Surface Markers: Current Status and Remaining Challenges for Characterization and Isolation. Front Cell  Dev Biol, in press. PubMed PMID: PMC6890603

Chen G, Abdeen AA, Wang Y, Shahi PK, Robertson S, Xie R, Suzuki M, Pattnaik BR, Saha K, Gong S (2019). A biodegradable nanocapsule delivers a Cas9 ribonucleoprotein complex for in vivo genome editing. Nature Nanotech, in press. PubMed PMID: 31501532

Lynch E, Semrad T, Belsito VS, FitzGibbons C, Reilly M, Hayakawa K, Suzuki M (2019)C9ORF72-related cellular pathology in skeletal myocytes derived from ALS-patient induced pluripotent stem cells. Dis Model Mech, 12(8).  PubMed PMID: 31439573.

Jiwlawat N, Lynch EM, Napiwocki BN, Stempien A, Ashton RS, Kamp TJ, Crone WC, Suzuki M (2019). Micropatterned substrates with physiological stiffness promote cell maturation and Pompe disease phenotype in human induced pluripotent stem cell-derived skeletal myocytes. Biotechnol Bioeng, 116(9):2377-2392. PubMed Central PMCID: PMC6699746.

Jeffrey J, D’Cunha H, Suzuki M (2018). Blood Level of Glial Fibrillary Acidic Protein (GFAP) Does not Correlate With Disease Progression in a Rat Model of Familial ALS (SOD1G93A Transgenic). Front Neurol, 9:954. PubMed Central PMCID: PMC6246740.

Jiwlawat N, Lynch E, Jeffrey J, Van Dyke JM, Suzuki M (2018). Current Progress and Challenges for Skeletal Muscle Differentiation from Human Pluripotent Stem Cells Using Transgene-Free Approaches. Stem Cells Int, 2018:6241681.  PubMed Central PMCID: PMC5924987.

Miyagoe-Suzuki Y, Asakura A, Suzuki M (2017). Skeletal Muscle Cells Generated from Pluripotent Stem Cells. Stem Cells Int, 2017:7824614. PubMed Central PMCID: PMC5642449.

Jiwlawat S, Lynch E, Glaser J, Smit-Oistad I, Jeffrey J, Van Dyke JM, Suzuki M (2017). Differentiation and sarcomere formation in skeletal myocytes directly prepared from human induced pluripotent stem cells using a sphere-based culture. Differentiation,  96:70-81. PubMed Central PMCID: PMC5669825.

Brunnquell CL, Hernandez R, Graves SA, Smit-Oistad I, Nickles RJ, Cai W, Meyerand ME, Suzuki M (2016). Uptake and retention of manganese contrast agents for PET and MRI in the rodent brain. Contrast Media & Molecular Imaging, 11(5):371-380. PMCID: PMC5140672.

Bernau K, Lewis CM, Petelinsek AM, Reagan MS, Niles DJ, Mattis VB, Meyerand ME, Suzuki M, Svendsen CN (2016). In vivo tracking of human neural progenitor cells in the rat brain using magnetic resonance imaging is not enhanced by ferritin expression. Cell Transplantation, 25: 575-92. PMCID: PMC5052815.

Van Dyke JM, Smit-Oistad IM, Macrandar C, Krakora D, Meyer MG, Suzuki M (2016). Macrophage-mediated inflammation and glial response in the skeletal muscle of a rat model of familial amyotrophic lateral sclerosis (ALS). Experimental Neurology, 277: 275-282.  PMCID: PMC4762214.

Lewis CM, Graves SA, Hernandez R, Valdovinos HF, Barnhart TE, Cai W, Meyerand ME, Nickles RJ, Suzuki M (2015). 52Mn production for PET/MRI tracking of human stem cells expressing divalent metal transporter 1 (DMT1). Theranostics, 5: 227-39. PMCID: PMC4279187.

Hosoyama T, McGivern JM, Van Dyke J, Ebert A, Suzuki M (2014). Derivation of myogenic progenitors directly from human pluripotent stem cells using a sphere-based culture. Stem Cells Translational Medicine, 3: 564-74. PMCID: PMC4006483.

Lewis CM, Suzuki M (2014). Therapeutic applications of mesenchymal stem cells for amyotrophic lateral sclerosis. Stem Cell Research & Therapy, 5: 32. PMCID: PMC4035799.

Van Dyke J, Suzuki M (2014). FGF-2: a critical factor for producing myogenic progenitors and skeletal muscle from pluripotent sources? Regenerative Medicine, 9: 405-7. PMID: 25159055

Krakora D, Mulcrone PL, Meyer M, Lewis CM, Bernau K, Gowing G, Zimprich C, Aebischer P, Svendsen CN, Suzuki M (2013). Synergistic effects of GDNF and VEGF on lifespan and disease progression in a familial ALS rat model. Molecular Therapy, 21: 1602-10. PMCID: PMC3734670.

Hosoyama T, Meyer MG, Krakora D, Suzuki M (2013). Isolation and in vitro propagation of human skeletal muscle progenitor cells from fetal muscle. Cell Biology International, 37: 191-6. PMCID: PMC3620662.

Nichols NL, Gowing G, Satriotomo I, Nashold LJ, Dale EA, Suzuki M, Avalos P, Mulcrone PL, McHugh J, Svendsen CN, Mitchell GS (2013). Intermittent hypoxia and stem cell implants preserve breathing capacity in a rodent model of ALS.  American Journal of Respiratory and Critical Care Medicine, 187: 535-42. PMCID: PMC3733409.

Nichols NL, Van Dyke J, Nashold L, Satriotomo I, Suzuki M, Mitchell GS (2013). Ventilatory control in ALS. Respiratory Physiology and Neurobiology, 189: 429-37. PMCID: PMC4361018.

Li R, Strykowski R, Meyer M, Mulcrone P, Krakora D, Suzuki M (2012). Male-specific differences in proliferation, neurogenesis, and sensitivity to oxidative stress in neural progenitor cells derived from a rat model of ALS. PLoS ONE, 7: e48581. PMCID: PMC3493558.

Hayes-Punzo A, Mulcrone P, Meyer M, McHugh J, Svendsen CN, Suzuki M (2012). Gonadectomy and dehydroepiandrosterone (DHEA) do not modulate disease progression in the G93A mutant SOD1 rat model of amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis, 13: 311-4. PMCID: PMC3644484.

Hosoyama T, Van Dyke J, Suzuki M (2012). Applications of skeletal muscle progenitor cells for neuromuscular diseases. American Journal of Stem Cells, 1: 253-63. PMCID: PMC3636729.

Krakora D, Macrander C, Suzuki M (2012). Neuromuscular junction protection for the potential treatment of amyotrophic lateral sclerosis. Neurology Research International, 379657. PMCID: PMC3423938.

Suzuki M, Klein S, Wetzel EA, Meyer M, McHugh J, Tork C, Hayes A, Svendsen CN (2010). Acute glial activation by stab injuries does not lead to overt damage or motor neuron degeneration in the G93A mutant SOD1 rat model of Amyotrophic Lateral Sclerosis. Experimental Neurology, 211: 346-52. PMCID: PMC2839070.

Riley J, Federici T, Park J, Suzuki M, McHugh J, Tork C, Franz CK, Teng Q, Svendsen CN, Boulis NM (2009). Cervical spinal cord therapeutic delivery: Preclinical safety validation of a stabilized microinjection platform. Neurosurgery, 65: 754-62. PMCID: PMC2764319.

Suzuki M, McHugh J, Tork C, Shelley B, Hayes A, Bellantuono I, Aebischer P, Svendsen CN (2008). Direct muscle delivery of GDNF with human mesenchymal stem cells improves motor neuron survival and function in a rat model of familial ALS. Molecular Therapy, 16: 2002-10. PMCID: PMC2678899.

Suzuki M, Svendsen CN (2008). Combining growth factor and stem cell therapy for Amyotrophic Lateral Sclerosis. Trends in Neurosciences, 32: 192-8.

Emborg ME, Ebert AD, Moirano J, Peng S, Suzuki M, Capowski E, Joers V, Roitberg BZ, Aebischer P, Svendsen CN (2008). GDNF-secreting human neural progenitor cells increase tyrosin hydroxylase and VMAT2 expression in MPTP-treated cynomolgus monkeys. Cell Transplantation, 17: 383-95.

Nelson A*, Suzuki M*, Svendsen CN (2008). A high concentration of epidermal growth factor (EGF) increases the growth and survival of neurogenic radial glial cells within human neurosphere cultures. Stem Cells, 26: 348-55.    *: Equally contributed.

Suzuki M, McHugh J, Tork C, Shelley S, Klein SM, Aebischer P, Svendsen CN (2007). GDNF secreting human neural progenitor cells protects dying motor neurons, but not their projection to muscle, in a rat model of familial ALS. PLoS ONE, 2: e689.

Suzuki M, Tork C, Shelley B, McHugh J, Klein SM, Lindstrom MJ, Svendsen CN (2007). Sexual dimorphism in disease onset and progression of a rat model of ALS. Amyotrophic Lateral Sclerosis, 8: 20-5.

Suzuki M, Nelson A, Eickstaedt J, Wallace K, Wright L, Svendsen CN (2006). Glutamate enhances proliferation and neurogenesis in human neural progenitor cell cultures derived from the fetal cortex. European Journal of Neuroscience, 24: 645-53.

Klein SM, Behrstock S, McHugh J, Hoffman K, Wallace K, Suzuki M, Aebischer P, Svendsen CN (2005). GDNF delivery using human neural progenitor cells in a rat model of ALS. Human Gene Therapy, 16: 509-21.

Suzuki M, Wright LS, Marwah P, Lardy HA, Svendsen CN (2004). Mitotic and neurogenic effects of dehydroepiandrosterone (DHEA) on human neural stem cell cultures derived from the fetal cortex. Proceedings of the National Academy of Sciences in the United States of America, 101: 3202-7.


Complete List of Published Work in MyBibliography:


Book chapters

Suzuki M. Progranulin in sexual differentiation of the developing brain. Progranulin, the therapeutic target for CNS and various disorders. (eds. H. Hara, M. Nishihara, T. Shimohata), pp105-116, Springer, 2019.

Glaser J, Suzuki M. Skeletal muscle fiber types in neuromuscular diseases. Muscle cell and tissue (ed. K. Sakuma), pp65-79, Intech, 2018.

Suzuki M, Svendsen CN. Ex vivo delivery of growth factors using human mesenchymal stem cells in the skeletal muscle of a familial ALS rat model. Gene Therapy for Neurological Disorders (ed. F.P. Manfredsson), Methods in Molecular Biology, 1382: 325-36, Humana Press-Springer. 2015.

Suzuki M, Tso C-F, Meyer MG. Stem Cell Application for Amyotrophic Lateral Sclerosis: Growth Factor Delivery and Cell Therapy (ed. M. Maurer), pp437-454, Intech, 2012.

Bernau K, Meyer MG, Suzuki M. Stem Cell Application in Amyotrophic Lateral Sclerosis: Growth factor delivery and cell therapy. Hormones in Neurodegeneration, neuroprotection and Neurogenesis (eds. I. Fedotova & V. Ilykhin), Nova publication, pp171-181, 2011.

Suzuki M, McHugh J, Kitiyanant N. Human neural progenitor cells: Mitotic and neurogenic effects of growth factors, neurosteroids, and excitatory amino acids. Hormones in Neurodegeneration, neuroprotection and Neurogenesis (eds. A. Gravanis & S. Mellon), Wiley-Blackwell, pp331-335, 2010.