Luis Fernandez
Medicine (Surgery)
Research Program
Improving the quality and insulin secretory capacity of human islets for transplantation. We have focused on creating a sensitive and specific expanded panel of assessments for human islets that provides a level of sensitivity and objectivity beyond the current FDA standard measures of islet identity, purity, viability, sterility, and functional potency. Other areas of interest: 1) evaluation of donor treatment strategies to improve the quality of islets from donation after brain death; and 2) evaluation of alternative donor sources for islet transplantation. In this regard, a strong interest in understanding beta cell biology from donation after cardiac death (DCD) donors as potential donors for beta cell therapy has been a major focus.
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