Department of Comparative Biosciences
Titles and Education
- Case Western Reserve University,Cleveland, OH 2001-02 Postdoctoral fellow Repro & Molecular Endocrinology
- Case Western Reserve University, Cleveland, OH 2001 PhD
- University of Wisconsin School of Veterinary Medicine 1993 DVM (with honors)
- University of Wisconsin, Madison, WI 1988 BS Biochemistry (with honors)
The Jorgensen lab uses cell and molecular biology tools to identify genes that are sexually dimorphic during sex differentiation, characterize their functional significance, and finally, understand how they are regulated. Currently, we are focusing on two genes: steroidogenic factor 1 (Sf1) and Iroquois homeobox factor 3 (Irx3).
Visit the JORGENSEN LAB WEBSITE for more information.
- Cellular and Molecular Biology
- Endocrinology Reproductive Biology Research Program
- Center for Women's Health Research
- Comparative Biomedical Sciences Graduate Program
- Molecular Pharmacology Graduate Program
Molecular and Environmental Toxicology Center
- Carney CM*, Muszynski JL*, Strotman LN*, Lewis SR, O’Connell RL, Beebe DJ, Theberge AB‡, Jorgensen JS‡. 2014 Cellular Microenvironment Dictates Androgen Production By Murine Fetal Leydig Cells In Primary Culture. Biol. Reprod. DOI.114.118570. [Epub ahead of print]
- Lewis SR, Hedman CJ, Ziegler T, Ricke WA, Jorgensen JS. 2014 Steroidogenic Factor 1 promotes aggressive growth of castration resistant prostate cancer cells by stimulating steroid synthesis and cell proliferation. Endocrinology, DOI:10.1210/en. 2013-1583.
- Jorgensen JS. 2013 Defining the neighborhoods that escort the oocyte through its early life events and into a functional follicle. Mol. Reprod. Dev., 80:960-976. PMID: 24105719. Selected for cover image.
- Kim B, Kim Y, Sakuma R, Hui CC, Rüther U, Jorgensen JS. 2011 Primordial germ cell proliferation is impaired in Fused Toes mutant embryos. Dev Biol 349:417-426. PMID: 20969841.
- Kim B, Kim Y, Cooke PS, Rüther U, Jorgensen JS. 2011 The Fused Toes locus is essential for somatic-germ cell interactions that foster germ cell maturation in developing gonads. Biol Reprod 84:1024-1032. PMID: 21293032. Selected for calendar image, 2012 BOR calendar