Alexandra (Alexa) J. Burton, BSc., BVSc., PhD, MRCVS, DACVIM (LAIM)

ajburton@wisc.edu

Department of Medical Sciences

Alexandra (Alexa) J. Burton, BSc., BVSc., PhD, MRCVS, DACVIM (LAIM)

Titles and Education

  1. BSc/BVSc, MRCVS 2004, University of Liverpool, United Kingdom.
  2. Diplomate of American College of Veterinary Internal Medicine, DACVIM (LAIM) 2009, Cornell University, U.S.A.
  3. PhD 2014, University of Georgia, U.S.A.

Research

Dr. Burton has published in numerous areas of large animal medicine, especially in the fields of infectious disease and pharmacology. Her current research interests are in the areas of equine pharmacokinetics and the history of large animal veterianry medicine in the context of present day antimicrobial stewardship and biosecurity.

Responsibilities

Dr. Burton is responsible for clinical service in large animal medicine (LAM) at the UW Veterinary Care Large Animal Hospital, working closely with the other LAM senior clinicians (Dr.s Peek, Marques and Holschbach). She is actively involved in the didactic and clinical instruction of veterinary students and with mentoring the UW-Vet Care LAM clinical residents.

Clinical Interests

Dr. Alexa Burton has broad clinical experience in large animal medicine, with a strong focus on individualized patient-centered care. In particular, she is has interests in critical care of all large animal species, equine senior/geriatric medicine and chronic and acute gastrointestinal disorders.
Dr. Burton also has experience in veterinary care of neonatal and adult camelids (alpacas and llamas).

Graduate Training

Dr. Alexa Burton received her veterinary degree from the University of Liverpool in the United Kingdom. She completed an internship in large animal medicine and surgery at the Ontario Veterinary College, University of Guelph, Canada. She then went on to a 3-year clinical residency in Large Animal Internal Medicine at Cornell University followed by the 2-year Cornell Clinical Fellowship program. Subsequently, Dr. Burton completed a PhD in Infectious Disease with Dr. Steeve Giguère at the University of Georgia (UGA) College of Veterinary Medicine, while also serving as a senior clinician in Large Animal Medicine at the UGA Veterinary Teaching Hospital.

Recent Publications

  1. Burton AJ. Successful treatment of wounded horses in World War 1, before the advent of antibiotics. ACVIM Forum Proceedings (Equine Scientific Sessions), Phoenix, AZ, June 6-8 2019.
  2. Giguère S, Burton AJ, Berghaus LJ, Haspel AD. Comparative pharmacokinetics of minocycline in foals and adult horses. J Vet Pharm Ther. 2017;40:335-341.
     
  3. Cohen ND, Giguère S, Burton AJ, Rocha JN, Berghaus LJ, Brake CN, Bordin AI, Coleman MC. Use of Liposomal gentamicin for treatment of 5 foals with experimentally induced Rhodococcus equi pneumonia. J Vet Intern Med. 2016;30:322-325.
  4. Burton AJ, Giguère S, Berghaus LJ, Hondalus MK. Activity of clarithromycin or rifampin alone or in combination against Rhodococcus equi infection in mice. Antimicrob Agents Chemother. 2015;59:3633-3636.
  5. Mullen KR, Furness MC, Johnson AL, Norman TE, Hart KA, Burton AJ, Bicahlo RC, Ainsworth DM, Thompson MS, Scrivani PV. Adverse reactions in horses that underwent general anesthesia and cervical myelography. J Vet Intern Med. 2015;29:954-960.
  6. Burton AJ. How to interpret antimicrobial susceptibility and minimum inhibitory concentration reports. AAEP Proceedings. 2015;61:152-153.
  7. Burton AJ, Giguère S, Berghaus LJ, Hondalus MK, Arnold RD. Efficacy of liposomal gentamicin against Rhodococcus equi in a mouse model and colocalization with R. equi in equine alveolar macrophages. Vet Micro. 2015;176:292-300.
  8. Burton AJ, Giguère S, Warner L, Alhamhoom Y, Arnold RD. Pharmacokinetics and tolerability of liposomal gentamicin and free gentamicin in foals. Equine Vet J. 2015;47:467-472.
  9. Burton AJ, Giguère S, Sturgill TL, Berghaus LJ, Slovis NM, Whitman JL, Levering C, Kuskie KR, Cohen ND. Macrolide- and rifampin-resistant Rhodococcus equi on a horse breeding farm, Kentucky, USA. Emerg Infect Dis. 2013;19:282-285.
  10. Burton AJ, Giguère S, Warner L, Alhamhoom Y, Arnold RD. Effect of age on the pharmacokinetics of a single daily dose of gentamicin sulfate in healthy foals. Equine Vet J. 2013;45:507-511.
  11. Zambriski JA, Nydam DV, Bowman DD, Bellosa ML, Burton AJ, Linden TC, Liotta JL, Ollivett TL, Tondello-Martins L, Mohammed HO. Description of fecal shedding of Cryptosporidium parvum oocysts in experimentally challenged dairy calves. Parasitol Res. 2013;112:1247-1254.
  12. Hart JC, Burton AJ, Pinn TL, Fubini SL, Dawson DR. Spiral colon impaction in juvenile alpacas: 12 cases (2006-2010). J Am Vet Med Assoc. 2013;242:1419-1424.
  13. Perkins GA, den Bakker H, Burton AJ, Erb H, McDonough SP, McDonough PL, Parker J, Rosenthal RL, Wiedmann M, Dowd S, and Simpson KW. The equine stomach harbors an abundant and diverse mucosal microbiota. Appl Environ Microbiol. 2012;78:2522-2532.
  14. Burton AJ, Nydam DV, Mitchell K, Bowman DD. Cryptosporidium shedding in alpaca crias and their dams in the New York State area. J Am Vet Med Assoc. 2012;241:496-498.
  15. Credille BC, Giguère S, Berghaus LJ, Burton AJ, Sturgill TL, G. Scott Grover GS, Donecker JM, Brown SA. Plasma and pulmonary disposition of ceftiofur and its metabolites after intramuscular administration of ceftiofur crystalline free acid in weanling foals. J Vet Pharmacol Ther. 2012;35:259-264.
  16. Burton AJ, Nydam DV, Jones G, Zambriski JA, Linden TC, Cox G, Davis R, Brown A, Bowman DD. Antibody responses following administration of a Cryptosporidium parvum rCP15/60 vaccine to pregnant cattle. Vet Parasitol. 2011;175:178-181.
  17. Burton AJ, Nydam DV, Dearen TK, Mitchell K, Bowman DD, Xiao L. The prevalence of Cryptosporidium, and identification of the Cryptosporidium horse genotype in foals in New York State. Vet Parasitol. 2010;174:139-144.
  18.  Johnson AL, Burton AJ, Sweeney RW. Utility of 2 immunological tests for antemortem diagnosis of equine protozoal myeloencephalitis (Sarcocystis neurona infection) in naturally occurring cases. J Vet Intern Med. 2010;24:1184-1189.
  19. Burton AJ, Nydam DV, Long ED, Divers TJ. Signalment and clinical complaints initiating hospital admission, methods of diagnosis, and pathological findings associated with bovine lymphosarcoma (112 cases). J Vet Intern Med. 2010;24:960-964.
  20. Wagner B, Burton A, Ainsworth D. Interferon-gamma, interleukin-4 and interleukin-10 production by T helper cells reveals intact Th1 and regulatory TR1 cell activation and a delay of the Th2 cell response in equine neonates and foals. Vet Res. 2010;41:47.
  21. Burton A, Wagner B, Erb HN, Ainsworth DM. Serum interleukin-6 (IL-6) and IL-10 concentrations in normal and septic neonatal foals. Vet Immunol Immunopathol. 2009;132:122-128.
  22. Burton AJ, Nydam DV, Ollivett TL, Divers TJ. Prognostic indicators for nonambulatory cattle treated by use of a flotation tank system in a referral hospital: 51 cases (1997-2008). J Am Vet Med Assoc. 2009;234:1177-1182.
  23. Saulez MN, Burton A, Steyl JC, Williams JH, Clift SJ. Perforation of the gastrointestinal tracts of four horses by metallic wires. Vet Rec. 2009;164:86-88.