Golos Lab


Below are representative publications from the major areas we have been studying over the years in the Golos lab.  A full list of published work can be found in My Bibliography, maintained by the US National Library of Medicine.


Burleigh, D.W., C.M. Kendziorski, Y.J. Choi, K.M. Grindle, R.L. Grendell, R.R. Magness and T.G. Golos. 2007. Microarray analysis of BeWo and JEG3 trophoblast cell lines: identification of differentially expressed transcripts. Placenta 28:383-389.

Bondarenko G.I., Burleigh D.W., Durning M., Breburda E.E., Grendell R.L., and T.G. Golos. 2007. Passive Immunization against the MHC Class I Molecule Mamu-AG Disrupts Rhesus Placental Development and Endometrial Responses. J. Immunol. 179:8042-8050.

Dambaeva, S.V., Bondarenko, G.I., Grendell R.L., Kravitz, R.H., Durning, M., and T.G. Golos. 2008. Nonclassical MHC-E (Mamu-E) expression in the rhesus monkey placenta. Placenta 29:58-70. PMCID: PMC2754872

Drenzek J.G., Breburda E.E., Burleigh D.W., Bondarenko G., Durning, M., and T.G. Golos. 2008. Expression of indoleamine 2,3-dioxygenase in the rhesus monkey and common marmoset reproductive tracts. J. Reprod. Immunol. 78:125-133.

Dambaeva, S.V., Breburda, E.E., Durning, M., Garthwaite, M.A., and T.G. Golos. 2009. Characterization of decidual leukocyte populations in cynomolgus and vervet monkeys. J. Reprod. Immunol. 80:57-69. PMCID: PMC3076217

Douglas, G.C., C.A. VandeVoort, P. Kumar, T.C. Chang, and T.G. Golos, 2009. Trophoblast stem cells: Models for Investigating Trophectoderm Differentiation and Placental Development. Endocrine Reviews. 30:228-40. PMCID: PMC2726840

Thomas C.P., J.I. Andrews, N.S. Raikwar, E.A. Kelley, F. Herse, R. Deschend, T.G. Golos, and K.Z. Liu. 2009. A recently evolved novel trophoblast-enriched secreted form of fms-like tyrosine kinase-1 variant is upregulated in hypoxia and in preelcampsia. J. Clin. Endo. Metab. 94:2524-2530. PMCID: PMC2708964

Bondarenko G.I., Dambaeva S.V., Grendell R.L., Hughes A.L., Durning, M., Garthwaite M.A., and T.G. Golos. 2009. Characterization of cynomolgus and vervet monkey placental MHC class I expression: Diversity of the nonhuman primate AG locus. Immunogenetics 61:431-442. PMCID: PMC2810720

Drenzek J.G., Vidiguriene J., Vidiguris G., Grendell R.L., Dambaeva S.V., Durning M., and T.G. Golos. 2009. Suppression of Mamu-AG by RNA interference. Am. J. Reprod. Immunol. 61: 453–461. PMCID: PMC2889004

Rozner, A.E., Dambaeva, S.V., Drenzek, J.G., Durning, M., and Golos, T.G. 2009 Generation of macrophages from peripheral blood monocytes in the rhesus monkey. J. Immunol. Methods 351:36-40. PMCID: PMC3564589

Golos, T.G., Bondarenko G.I., Dambaeva, S.V., Breburda, E.E., and M. Durning. 2010. On the role of placental major histocompatibility complex and decidual leukocytes in implantation and pregnancy success using non-human primate models. Int. J. Dev. Biol. 54:431-443. Review. PMCID: PMC3069127

Giakoumopoulos, M., Siegfried, L.M. Dambaeva, S.V., Garthwaite, M.A., and T.G. Golos. 2010 Placental-derived mesenchyme influences chorionic gonadotropin and progesterone secretion of human embryonic stem cell-derived trophoblasts. Reproductive Sciences. 17(9):798-808. NIHMSID: NIHMS282437. PMCID: PMC3065864

Zhang X., Pankratz M.T., Chen J., Xi J., Li J., Yang Y., LaVaute T.M., Li, X.-J., Ayala M., Bondarenko G.I., Du Z.-W., Huang C.T., Jin Y., Golos T.G., and S.-C. Zhang. 2010. Pax6 is a Human Neuroectoderm Cell Fate Determinant. Cell Stem Cell. 7(1):90-100. PMCID: PMC2904346.

Rozner, A.E., Dambaeva, S.V., Drenzek, J.G., Durning, M., and Golos, T.G. 2011. Modulation of Cytokine and Chemokine Secretion in Rhesus Monkey Trophoblast Co-Culture with Decidual but not Peripheral Blood Monocyte-Derived Macrophages. Am. J. Reprod. Immunol. 66:115-127. PMCID: PMC3132823.

S.V. Dambaeva, M. Durning, A.E. Rozner, and T.G. Golos. 2012. Immunophenotype and Cytokine Profiles of Rhesus Monkey CD56bright and CD56dim Decidual Natural Killer (NK) Cells. Biol. Reprod. 86: 1-10. PMCID: PMC3313663

Padua, MB, Lynch VJ, Alvarez NV, Garthwaite MA, Golos, TG, Bazer FW, Kalkunte S, Sharma, S, Conrad, KP, and Hansen, PJ. 2012 ACP5 (Uteroferrin): Phylogeny of an Ancient and Conserved Gene Expressed in the Endometrium of Mammals. Biol. Reprod. 86(4):123, 1-8. PMCID: PMC3338662

Home, P., Saha, B., Vivian, J.L., Dutta, D., Ray, S., Gunewardena, S., Yoo, B., Larson, M., Wolfe, M.W., Petroff, M., Gallagher, P.G., Schulz, V., White, K.L., Golos, T.G., Rozner, A.E., Durning, M., Behr, B., and Paul, S. 2012. Altered sub-cellular localization of transcription factor TEAD4: An evolutionary conserved mechanism to regulate first mammalian cell-lineage commitment. PNAS. 109:7362-7. PMCID: PMC3358889

Bondarenko, GI, Durning M, Golos TG. 2012. Immunomorphological changes of rhesus monkey endometrium during the menstrual cycle and early pregnancy. Am. J. Reprod. Immunol. 68:309-21. PMCID: PMC3440518

Ahmed MS, et al. 2012 IFPA Meeting 2012 Workshop Report II: Epigenetics and imprinting in the placenta, growth factors and villous trophoblast differentiation, role of the placenta in regulating fetal exposure to xenobiotics during pregnancy, infection and the placenta. Placenta. 12: 455-9.

Giakoumopoulos M, Golos TG. 2013. Embryonic stem cell-derived trophoblast differentiation: a comparative review of the biology, function, and signaling mechanisms. J. Endocrinol. 216: R33-R45.

Chopra P, Papale LA, White ATJ, Hatch A, Brown RM, Garthwaite MA, Roseboom PH, Golos TG, Warren ST, Alisch RS. 2014. Array-based assay detects genome-wide 5-mC and 5-hmC in the brains of humans, non-human primates, and mice. BMC Genomics. 15:131. doi: 10.1186/1471-2164-15-131. PMID: 24524199 PubMed – in process]

Poulsen KP, Faith NG, Golos TG, Giakoumopoulos M, Czuprynski CJ. 2014 Listeria monocytogenes infection reduces the functionality of human choriocarcinoma JEG-3 cells. J. Neonatal Biol. 3:125. doi: 10.4172/2167-0897.1000125.

Iruretagoyena JI, Davis W, Bird C, Olsen J, Radue R, Broman AT, Kendziorski C, Bondurant SS, Golos T, Bird I, Shah D. 2014 Differential changes in gene expression in human brain during late first trimester and early second trimester of pregnancy. Prenat Diagn. 34: 431-437.

Iruretagoyena JI, Davis W, Bird C, Olsen J, Radue R, Broman AT, Kendziorski C, Bondurant SS, Golos T, Bird I, Shah D. 2014. Differential Changes in Gene Expression in Human Heart during Late First Trimester and Early Second Trimester of Pregnancy. Mol. Human Reprod. 20: 690-700.

Prabhudas M, et al. 2015. Immune mechanisms at the maternal-fetal interface: perspectives and challenges. Nat. Immunol. 16: 328-34.

Barbaux S, et al. 2015. IFPA meeting 2014 workshop report: Animal models to study pregnancy pathologies; new approaches to study human placental exposure to xenobiotics, biomarkers of pregnancy pathologies; placental genetics and epigenetics; the placenta and stillbirth and fetal growth restriction. Placenta. 36 Suppl 1:S5-10.

Dudley DM, Aliota MT, Mohr EL, Weiler AM, Lehrer-Brey G, Weisgrau KL, et al. Natural history of Asian lineage Zika virus infection in macaques. bioRxiv. 2016.

Dudley DM, Aliota MT, Mohr EL, Weiler AM, Lehrer-Brey G, Weisgrau KL, et al. A rhesus macaque model of Asian-lineage Zika virus infection. Nat Commun. 2016;7:12204.

Rozner AE, Durning M, Kropp J, Wiepz GJ, Golos TG. Macrophages modulate the growth and differentiation of rhesus monkey embryonic trophoblasts. Am J Reprod Immunol. 2016;76(5):364-75.

Aliota MT, Bassit L, Bradrick SS, Cox B, Garcia-Blanco MA, Gavegnano C, et al. Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network. Antiviral Res. 2017;144:223-46.

Kropp J, Di Marzo A, Golos T. Assisted reproductive technologies in the common marmoset: an integral species for developing nonhuman primate models of human diseases. Biol Reprod. 2017;96(2):277-87.

Nguyen SM, Antony KM, Dudley DM, Kohn S, Simmons HA, Wolfe B, et al. Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques. PLoS Pathog. 2017;13(5):e1006378.

Reyes L, Wolfe B, Golos T. Hofbauer Cells: Placental Macrophages of Fetal Origin. Results Probl Cell Differ. 2017;62:45-60.

Vermilyea SC, Guthrie S, Meyer M, Smuga-Otto K, Braun K, Howden S, et al. Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts. Stem Cells Dev. 2017;26(17):1225-35.

Wolfe B, Wiepz GJ, Schotzko M, Bondarenko GI, Durning M, Simmons HA, et al. Acute Fetal Demise with First Trimester Maternal Infection Resulting from Listeria monocytogenes in a Nonhuman Primate Model. MBio. 2017;8(1).

Aliota MT, Dudley DM, Newman CM, Mohr EL, Gellerup DD, Breitbach ME, et al. Heterologous Protection against Asian Zika Virus Challenge in Rhesus Macaques. PLoS Negl Trop Dis. 2016;10(12):e0005168.

Chapters In Books:

Golos, T.G. 2011. Stem Cells From the Placenta. In: The Placenta: from Development to Disease. Wiley-Blackwell, H. Kay, D. Michael Nelson and Y. Wang (eds), West Oxford, UK.

Hélène Marquis, Douglas A. Drevets, Michael S. Bronze, Sophia Kathariou, Thaddeus G. Golos, J. Igor Iruretagoyena. 2015. Pathogenesis of Listeria monocytogenes in human. In: Emerging and Re-emerging Human Infections. John Wiley & Sons/Wiley Blackwell Press, pp 747-770.