Comparative Orthopaedic Research Laboratory

Canine Studies

Clinical Research in Canine Orthopedics

Genotypic Dissection of Osteosarcoma in Irish Wolfhounds

The purpose of this study is to identify a genetic mutation associated with osteosarcoma in dogs and use this information to develop a means to predict risk.

Genotypic Dissection of Laryngeal Paralysis in Dogs

The purpose of this study is to identify genetic mutations that are associated with the laryngeal paralysis condition in dogs and use this information to develop a genetic test for the condition. [Laryngeal Paralysis Brochure]  [Laryngeal Paralysis Flyer]

Genotypic Dissection of Cruciate Rupture in Dogs

The purpose of this study is to identify genetic mutations that are associated with the non-contact cranial cruciate rupture condition in dogs and use this information to develop a genetic test for the condition. [Cruciate Ligament Brochure] [Cruciate Ligament Flyer]

Genetics of Fibrotic Myopathy in the German Shepherd Dog

The purpose of this study is to identify genetic mutation associated with the fibrotic myopathy condition in dogs and use this information to develop a genetic test for the condition.
Read about the Fibrotic Myopathy Research

Measuring the Treatment Effects of an Immunomodulator in Naturally-Occurring Elbow Osteoarthritis in Dogs

Enrollment is now complete. The purpose of this study is to determine whether an immunomodulator treatment can improve the degree of lameness and reduce joint inflammation in dogs affected with elbow osteoarthritis (OA) as a consequence of fragmented medial coronoid process (FCP). This treatment aims to suppress the main cell types responsible for osteoarthritic inflammation. The treatment will be administered by intra-articular injection into the affected elbow joint. [Elbow Immunomodulator Brochure] [Elbow Immunomodulator Flyer]

Comprehensive Assessment of Bone Deformities in Dogs

This work is focused on improving assessment of limb alignment in dogs using radiography, CT, and 3D biomodels. This research allows the Small Animal Orthopedic service to print 3D biomodels for surgical planning.
 [Link for more information on assessment of bone deformities in dogs]

Evaluation of Hybrid Locking Bone Plates for Fractures

This study is investigating the biomechanical properties of various configurations of locking and nonlocking bone plates in canine synthetic bone and cadaver bone models. This work will inform clinical application of locking plates for treatment of long bone fractures.

Force Platform Gait Analysis in Heterogeneous Populations of Dogs

Several clinical research studies using force platform gait analysis are underway investigating gaits and gait analysis in diverse populations of dogs with an assortment of conditions.

Clinical Studies at UW Vet Care Hospital