Comparative Orthopaedic Research Laboratory

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The Comparative Genetics and Orthopedic Research Lab

An Introduction

The Comparative Genetics and Orthopedic research lab is a multidisciplinary research group focused on solving genetic and orthopedic problems that affect animals and humans. The laboratory is located in the School of Veterinary Medicine, University of Wisconsin-Madison. One of the laboratory’s greatest attributes is the strong collaborative relationships that exist between the laboratory, the School of Medicine and the College of Engineering. Financial support for the laboratory includes both federal and non-federal funding agencies, medical and veterinary foundations, corporate partners, and private donors. This website is designed to give a broad introduction to our research efforts.

Current Research

The genetics of Laryngeal Paralysis, the genetics of Cranial Cruciate Ligament Rupture (ACL Tear), the genetics of Degenerative Suspensory Ligament Disease (DSLD) in the Horse, stress fracture and functional bone adaptation as well as numerous force platform gait analysis and animal model / surgical investigations, Genetics of Osteosarcoma, Genetics of Fibrotic Myopathy, Genetics of Tooth Resorption in mesocephalic cats

Past Research

Fracture repair and augmentation, cartilage resurfacing, hip dysplasia, total hip replacement, canine shoulder disease, nutraceutical supplement therapy for arthritis, osteoarthritis, inflammatory arthritis and thermal treatment of musculoskeletal tissues, bone deformities in dogs, evaluation of hybrid locking bone plates,  immunomodulatory therapy for arthritis, the etiopathogenesis of cranial cruciate rupture, Neurofilament Light Chain Study.