By Kelly April Tyrrell On January 31, 2019, an 11-year old boy in Japan went to a medical clinic with a fever. The providers there diagnosed him with influenza, a strain called H3N2, and sent …
Research News
Common Chemical Linked to Rare Birth Defect in Mice
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A chemical commonly used in consumer and agricultural products to boost the effectiveness of insecticides has been linked to a rare birth defect in mice. The chemical, piperonyl butoxide or PBO for short, is widely used as a “synergist” in household and agricultural insecticides to make the toxic effects of the insecticide longer lasting and to reduce the amount of actual insecticide in a product.
Despite its widespread and growing use, as well as its ubiquity in the environment, the chemical has been little studied. Now, a team led by Robert Lipinski, a professor of comparative biosciences in the University of Wisconsin–Madison’s School of Veterinary Medicine, reports that PBO interferes with the critical signaling pathway dubbed by scientists as sonic hedgehog, resulting in stunted forebrain development and signature facial abnormalities. The study is published this week (Oct. 23, 2019) in the journal Environmental Health Perspectives.
Tiny Capsules Packed With Gene-Editing Tools Offer Alternative to Viral Delivery of Gene Therapy
Posted onNew tools for editing genetic code offer hope for new treatments for inherited diseases, some cancers, and even stubborn viral infections. But the typical method for delivering gene therapies to specific tissues in the body …
Summer Scholars Present Research, Alumna Awarded at National Veterinary Symposium
Posted onThe UW School of Veterinary Medicine (SVM) was well represented at the 2019 National Veterinary Scholars Symposium in Worcester, Massachusetts in July. Twenty-two doctor of veterinary medicine (DVM) students from UW participated in the symposium …
Veterinarians, Physicians to Jointly Explore Links Between Animal and Human Health
Posted onA physician, a veterinarian and a PhD researcher walk into a conference. At the event’s conclusion, the medical doctor says: “I had no idea there were veterinary cardiologists like there are human cardiologists.” This interaction …
From Immersive Education to Crane Rehabilitation, SVM Researchers Earn 2019 Global Health Grants
Posted onTackling everything from mosquitoes to antibiotic resistance, the University of Wisconsin-Madison Global Health Institute (GHI) recently awarded 30 grants and awards to faculty, staff, clinicians and students from across campus, including three recipients from the …
UW-Madison Global Health Institute Named Global Virus Network Center of Excellence; SVM Faculty to Co-Direct
Posted onThe University of Wisconsin-Madison Global Health Institute (GHI) has been named a Center of Excellence in the Global Virus Network (GVN). Tony Goldberg and Yoshi Kawaoka, professors in the UW School of Veterinary Medicine Department of Pathobiological …
Amid Massive Die-Offs, New Look at Saving Freshwater Mussels
Posted onFlowing out of the southern Appalachians, the Clinch River winds between mountains covered by forests and dotted with small farms. Here in southwestern Virginia’s coal country, forests blaze in reds, oranges and yellow each fall. …
Clinical Trial Begins to Test Universal Vaccine Against Canine Cancer
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Dogs started receiving a vaccine against cancer this week in a clinical trial at the UW-Madison School of Veterinary Medicine. If the vaccine works in dogs, it may not only provide a new strategy for addressing a critical canine health concern, it might also work in people.
Study: Vaccines Could Prevent Cancer in Dogs, Eventually Humans
Posted on Wisconsin State Journal
A "paradigm shift" in cancer research, the new technology could prevent cancer from developing by training the immune system to kill cells while they're small. Three veterinary centers from across the country, including the UW School of Veterinary Medicine, are participating in the five-year study — the largest clinical trial of a veterinary medicine in history.