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Pneumocystis carinii |
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- Formerly considered a protozoan, grows as a cyst-like form in lung tissue. Doesn’t grow in vitro
- Foamy interstitial pneumonitis when CMI defective, scourge of AIDS patients.
- Common in most mammalian species, thought to be transmitted by aerosol.
- Can occur in stressed lab animals.
- Treat with sulfa/trimethoprim, pentamidine.
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Protothecosis |
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- Prototheca zopfii (animals)
- P. wickerhamii (in humans).
- Thought to be an algae that lost chlorophyll.
- Multinucleated yeast-like organism on agar.
- Cattle - mastitis, enterocolitis
- Dogs - enterocolitis, abscesses
- Humans - progressive soft tissue infection
- Treatment - very resistant, surgical excision
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Rhinosporidiosis |
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- Rhinosporidium seeberi
- forms spherules with endospores in tissue
- Vascularized polyps in nose and conjunctiva
- Can only grow in tissue culture in vitro
- Associated with water, polyps are chronic
- Reported to occur in horses, cattle, dogs, ducks, humans
- Resistant to treatment - surgically excise
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