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Nicholas L. Abbott, Ph.D.
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Dr. Abbott is a Professor of Chemical Engineering at the University of Wisconsin-Madison. His research interests span colloid, interface, and surfactant science. A particular focus is directed towards the design of new surfactants that can be placed under active control, the use of liquid crystalline materials to amplify biomolecular interactions, and the design of interfaces with chemistry and topography patterned on nanometer dimensions. His work has been recognized by honors, which include a Presidential Early Career Award in Science and Engineering, a Camille Dreyfus Teacher-Scholar Award and a Fulbright Fellowship. He has published in leading journals, including Science, Journal of the American Chemical Society, Physical Review Letters and Langmuir.
Elizabeth Adkins, DVM, MS, DACVO
Dr. Adkins is a board-certified veterinary ophthalmologist and was a clinical instructor at the School of Veterinary Medicine, University of Wisconsin-Madison. Currently she is the staff ophthalmologist at the Hope Center for Advanced Veterinary Medicine in Vienna, Virginia. Her clinical and research interests include ocular pharmacology, cataractogenesis and cataract surgery.
Ralph M. Albrecht, Ph.D.
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Dr. Albrecht holds faculty appointments in Pharmaceutical Sciences, Animal Health & Biomedical Sciences, and Pediatrics at the University of Wisconsin-Madison. He is the Director of the BBPIC/AMFSC Microscopy Lab. His research activities lie in the area of cell surface receptors and antigens; receptor-cytoskeleton interactions; structure/function relationships in platelets and macrophages; correlative cell cytology, cytochemistry, and ultrastructure; video-enhanced DIC light microscopy, scanning electron microscopy, high voltage electron microscopy; immuno-gold and ligand-gold preparations and labeling for light and electron microscopy; and biocompatibility of polymer surfaces.
Michael Altaweel, M.D.
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Dr. Altaweel is an Assistant Professor of Ophthalmology at the University of Wisconsin School of Medicine and Public Health. He specializes in diseases and surgery of the retina and vitreous, and fundus interpretation. Dr. Altaweel is a Co-director of the University of Wisconsin Department of Ophthalmology Fundus Photograph Reading Center. His research interests include clinical trials of drug efficacy as well as the scientific grading of retinal photographs and fluorescein angiograms.
David R. Andes, MD
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Dr. Andes is an Assistant Professor in the Department of Medicine at the University of Wisconsin School of Medicine and Public Health. His research is focused on examining the relationships between antimicrobial pharmacodynamics and drug resistance, and identifying new antimicrobial drug treatment strategies and drug targets using in-vitro and animal infection models. His laboratory also works with clients to develop animal infection models. These models provide a useful phenotypic screen for gene disruption studies to identify virulence determinants in various pathogens. These animal infection models are also useful for early testing of novel anti-infective compounds.
Robert Auerbach, Ph.D.
Dr. Auerbach is the Harold R. Wolfe Professor of Zoology, a member of the Institute on Aging and Associate Member of the Wisconsin Clinical Cancer Center at the University of Wisconsin-Madison. He is widely recognized as a pioneer in the area of angiogenesis and endothelial cell differentiation. He has developed specialized techniques for the assessment of angiogenesis in vivo including the mouse corneal angiogenesis model and the intradermal skin assay. His in vitro research has led to the isolation of a large number of organ-specific endothelial cell lines, including lines established from retinal, corneal, and choroidal blood vessels. His current research focuses on differential angiogenesis in the eye and on endothelial cell heterogeneity.
Neal Barney, M.D.
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Dr. Barney is an Associate Professor in the Department of Ophthalmology and Visual Sciences at the University of Wisconsin School of Medicine and Public Health. His clinical training is in all aspects of ocular immunology to include uveitis and inflammatory disease of the anterior segment of the eye. His laboratory interests include the cellular signaling events on the ocular surface undergoing allergic reactions. He is the principle investigator for NIH funded research.
Ellison Bentley, D.V.M., MS, DACVO
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Dr. Bentley is a board certified Veterinary Ophthalmologist and a Clinical Associate Professor at the School of Veterinary Medicine, University of Wisconsin-Madison. Her clinical and research interests include corneal wound healing, particularly in spontaneous models of recurrent erosions. She has additional training in clinical trails, with an interest in effective management of pain in clinical patients. Other research interests are ocular imaging, with a focus on high resolution ultrasound, and glaucoma.
Paul J. Bertics, Ph.D.
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Dr. Bertics is a Professor of Biomolecular Chemistry at the University of Wisconsin-Madison. His research interest is in the biology of cellular signaling. Using the epithelial growth factor receptor and macrophage activation as models, he studies the determinants involved in specifying and regulating the function of receptor interaction and cellular activation. Techniques such as high-throughput screening for cell signaling antagonists and rational drug design are also integral to the lab's specialties.
Curtis R. Brandt, Ph.D.
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Dr. Brandt is a Professor in the Department of Ophthalmology and Visual Sciences, Medical Microbiology and Immunology, and University of Wisconsin Clinical Cancer Center at the University of Wisconsin-Madison. His research interest is virology, specifically pathogenesis of herpes simplex virus; virulence genes in herpetic eye disease and herpes encephalitis; antivirals; interactions between cytokines and herpes viruses, and gene delivery, gene therapy.
Craig E. Crosson, Ph.D.
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Dr. Crosson is a Professor and Vice Chairman for Research in the Department of Ophthalmology at the Medical University of South Carolina (MUSC). He is also the Director of the Ola B. Williams Glaucoma Therapeutic Development Center at MUSC and Director of Research at the Albert Florens Storm Eye Institute at MUSC. His research interests include ischemia, neovascularization, and glaucoma. Current research in his laboratory includes pharmacological treatment of elevated intraocular pressure and the use of retinal as a probe of the structure and function of retinoid binding proteins.
Ronald Danis, M.D.
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Dr. Danis is a Professor in the Department of Ophthalmology and Visual Sciences and Director of the Fundus Photograph Reading Center, University of Wisconsin-Madison. Dr. Danis has performed pre-clinical research employing a variety of animal models of intraocular angiogenesis, including laser-induced choroidal neovascularization, oxygen-induced retinopathy, and ischemia-induced retinal neovascularization. He has been a preclinical investigator in a variety of therapeutic efforts, including photodynamic therapy, and systemic, periocular, and intravitreal administration of compounds. He also has had experience as a clinical investigator in many clinical trials of retinal diseases.
Yuri P. Danilov, MS, PhD
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Dr. Danilov is a neuroscientist with over 30 years experience in research on brain function and the special senses, including vision, taste, and balance. Dr. Danilov is the lead discoverer of the balance retention effect, lead development of the specific training regimens, and continues to identify potential clinical and non-clinical application of neuromodulation and sensory substitution technology. Dr. Danilov received his M.S. degree in biophysics, in 1978, from St. Petersburg University in Russia and his Ph.D. degree in neuroscience, in 1984, from the Pavlov Instititute of Physiology, Russian Acadamy of Science. Dr. Danilov is Senior Scientist in the Orthopedics and Rehabilitation Medicine Department, University of Wisconsin School of Medicine and Public Health. His interest areas are neuroplasticity, neurorehabilitation, and sensory systems physiology.
Matthew D. Davis, M.D.
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Dr. Davis is Professor Emeritus of Ophthalmology and Vision Science at the University of Wisconsin Madison. He is widely recognized as an expert in the interpretation of clinical fundus images (including fluorescein and indocyanine green angiography). Additionally, he is the founder of the Fundus Photograph Reading Center, Department of Ophthalmology and Visual Sciences, University of Wisconsin Madison; an international resource for fundus interpretation.
Henry F. Edelhauser, Ph.D.
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Dr. Edelhauser is Professor of Ophthalmology and Director of Ophthalmic Research at Emory University School of Medicine, Atlanta, Georgia. He is widely recognized as an expert in corneal anatomy, physiology and toxicology. His primary research includes the pathogenesis of corneal edema after intraocular surgery, corneal and scleral permeability of therapeutic drugs to treat eye disease, ocular toxicology and development of new methods for transscleral drug delivery to the posterior segment. He has published over 270 peer reviewed scientific articles in three research areas.
Janis T. Eells, Ph.D.
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Dr. Eells is Associate Professor of Pharmacology and Toxicology at the University of Wisconsin-Milwaukee. Her expertise is in neurotoxicology and she is widely recognized as an expert in the mechanisms of retinal and optic nerve toxicity having served as an advisor and consultant to pharmaceutical companies, government agencies, and the World Health Organization in the area of ocular toxicity. She has a broad in-depth knowledge of physiology, pharmacology, neurobiology and toxicology with particular expertise in ocular toxicology. Her research program is focused on the mechanisms of retinal and optic nerve toxicity with an emphasis on the role of mitochondrial dysfunction and reactive oxygen species in retinal and optic nerve disease processes. Her laboratory has been involved in the development and evaluation of new technologies for the analysis and investigation of ion channel physiology, mitochondrial bioenergetics, retinal cell metabolism and photoreceptor function.
Ronald Engerman, Ph.D.
Dr. Engerman is Professor-Emeritus of Ophthalmology and Vision Science at the University of Wisconsin-Madison. His laboratory is internationally recognized for its pivotal role in the development of animal models of diabetic retinopathy that are widely utilized by companies concerning ocular toxicity.
Douglas Esson, MRCVS, DVM, DACVO
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Dr. Esson is a board certified veterinary ophthalmologist with Eye Care for Animals in California, the largest referral practice in the United States. His interests include glaucoma, neuro-protection and clinical research. He has authored scientific manuscripts and texts, published his research in journals including Veterinary Ophthalmology, the Journal of Glaucoma, Science, Investigative Ophthalmology and Visual Science and presented his material at ACVO, ARVO, AGS and AAO. Dr Esson has experience working with multiple laboratory and non-human primate species and he is available as a primary, in-house trials consultant.
Anne K. Goulding, BA
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Ms. Goulding is a Digital Imaging Specialist with the Fundus Photograph Reading Center, Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison. She has extensive knowledge in ophthalmic digital imaging systems as well as Optical Coherence Tomography. She has also performed training sessions for OCT technicians, non-mydriatic photography and slit-lamp photography.
Elizabeth Hennes, BS, MS
Mrs. Hennes is a researcher in the Department of Ophthalmology and Visual Sciences at the University of Wisconsin School of Medicine and Public Health. She has 7 years of experience in working with non-human primates in the department and three years in electrophysiology while working with a variety of species. Her particular research experience is in glaucoma and presbyopia.
Howard C Howland Ph.D.
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Dr. Howland is Professor of Neurobiology and Physiology at Cornell University. He is widely recognized as an expert in physiological optics and has worked extensively with animals and the development of the human infant visual system. He has developed many novel approaches for the evaluation of the optical system in vivo that have found wide application in studies of animals and humans.
Larry D. Hubbard, MA
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Mr. Hubbard is a researcher in the Department of Ophthalmology and Visual Sciences at the University of Wisconsin School of Medicine and Public Health. He is also Associate Director-Image Grading, Fundus Photograph Reading Center, Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison. His research has included developing an ordinal scale to express the severity of diabetic retinopathy and designing the Reading Center's grading program for evaluating treatment of an infection that can lead to blindness in AIDS patients.
Paul L. Kaufman, MD
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Dr. Kaufman is Professor and Chairman of the UW Department of Ophthalmology and Visual Sciences at the University of Wisconsin School of Medicine and Public Health. His research centers on studies of the physiology, pharmacology, morphology, cell biology, genetic manipulation, neural control, biomechanics and aging of the aqueous humor formation and drainage and accommodative mechanisms in the non-human primate, seeking to understand the pathophysiology and develop new therapies for the human diseases of glaucoma and presbyopia.
Charlene Kim, Ph.D.
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Dr. Kim is a researcher in the Department of Ophthalmology and Visual Sciences at the University of Wisconsin School of Medicine and Public Health. She has over 15 years of experience in electrophysiology and has worked with a wide array of vertebrate species investigating the electrophysiology of the eye. She has particular experience in the aging eye and glaucoma.
Eugene E. Knutson, BA
Mr. Knutson is the Ophthalmic Photography Manager at the University of Wisconsin Hospital Eye Clinic (University Station Clinics) in Madison. His daily activities include retinal fluorescein angiography, color fundus photography, optical coherence tomography, corneal topography, slit lamp biomicrography and external photos for the ocular plastics service.
Len Levin, M.D., Ph.D.
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Dr. Levin is a fellowship-trained board-certified Neuro-Ophthalmologist at the University of Wisconsin School of Medicine and Public Health who specializes in diseases of the optic nerve. He also received a PhD in Neurobiology, and his laboratory studies optic neuropathies and retinal ganglion cell death at the molecular, biochemical, and cellular level. He has served as a consultant to pharmaceutical companies in the areas of neuroprotection and its application to human disease, including glaucoma.
Mark J. Lucarelli, MD
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Dr. Lucarelli is an Associate Professor in the Department of Ophthalmology and Visual Sciences, University of Wisconsin – Madison, where he is Director of the Oculoplastics Service. Dr. Lucarelli is recognized as a leader within his field which specializes in disorders of the eyelids, lacrimal system, orbit, and related facial structures. His research interests center on surgical techniques and anatomic studies of the periocular structures. Dr. Lucarelli has a special interest in thyroid eye disease (Graves' orbitopathy) and serves on the recently founded Steering Committee of the International Thyroid Eye Disease Study Group (ITEDS).
Jonathon F. McAnulty, D.V.M., Ph.D.
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Dr. McAnulty is an Associate Professor of Surgery at the School of Veterinary Medicine, University of Wisconsin–Madison. He is a general surgeon with an expertise in microvascular surgery, solid organ transplantation, and organ preservation. Dr. McAnulty, in collaboration with Dr. Christopher Murphy, has validated a model of delayed skin wound healing for the testing of compounds that stimulate the healing of wounds.
Gillian J. McLellan, BVMS, PhD
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Dr. McLellan is a board–certified veterinary ophthalmologist and holds both an Associate Scientist position in the Department of Ophthalmology and Visual Sciences, School of Medicine and Public Health, and a Clinical Instructor position in the School of Veterinary Medicine, University of Wisconsin-Madison. Dr McLellan’s main clinical and research emphasis lies in comparative glaucomatology. Her current research focuses on the characterization of the genetic basis, clinical progression and pathological features of spontaneous animal models of glaucoma.
Paul E. Miller, D.V.M., DACVO
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Dr. Miller is a board certified Veterinary Ophthalmologist and a Clinical Professor at the School of Veterinary Medicine, University of Wisconsin-Madison. His research and clinical interests focus on glaucoma in animals and, recently, he has worked extensively with non-human primate models of glaucoma. He is the Chairman of the multi-center clinical trial committee of the American College of Veterinary Ophthalmologists.
Michael W. Neider, B.A.
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Mr. Neider is Associate Director-Photographic Services, Fundus Photograph Reading Center, Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison. The reading center has extensive experience interfacing with industry in the interpretation of clinical trials as well as participating in pre-clinical studies.
Robert W. Nickells, Ph.D.
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Dr. Nickells is a Molecular Biologist who specializes in intracellular signaling pathways. His research utilizes the tools of molecular biology to investigate pathophysiologic processes of the retina and optic nerve. His current research focuses on glaucoma and neuroprotective mechanisms.
Charles A. O'Neill, Ph.D.
Charles A. O'Neill, PhD: Dr. O'Neill brings to CORL 14 years of biotechnology and pharmaceutical development experience. Dr. O'Neill led nonclinical development efforts regarding anti-angiogenic molecules including the targeted oncology monoclonal antibody AvastinTM, and the intra-vitreally delivered monoclonal antibody fragment LucentisTM a treatment for the neovascular form of age-related macular degeneration. Regarding the LucentisTM nonclinical development, Dr. O'Neill designed, implemented and analyzed nonclinical pharmacology and toxicology studies demonstrating the safety, dosing schedules, dosing levels and pharmacological activity of LucentisTM in various animal models and interacted with regulatory agencies regarding this nonclinical development. Currently, Dr. O'Neill is Assistant Adjunct Professor in the Pharmacology and Toxicology Graduate Group at UC Davis. Dr. O'Neill was a Postdoctoral Fellow at the NIH, NHLBI. Dr. O'Neill has contributed to 26 regulatory submissions in the US, EU, Australia and Japan and has coauthored over 40 peer-reviewed publications. Dr. O'Neill received his Ph.D. in Pharmacology and Toxicology from UC Davis in 1992 and has been a Diplomate of the American Board of Toxicology since 1995.
Todd Perkins, MD
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Dr. Perkins is a Professor in the Department of Ophthalmology and Visual Sciences at the University of Wisconsin School of Medicine a Public Health. His clinical training is in all aspects of glaucoma. His laboratory interests have included surgical devices and antimetabolites for the treatment of glaucoma.
Arthur S. Polans, Ph.D.
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Dr. Polans is an Associate Professor of Ophthalmology and Vision Science and Associate Professor of Biomolecular Chemistry at the University of Wisconsin-Madison. He is an expert in the Biochemistry and molecular biology of the eye. His research program encompasses diverse fields of investigation including ocular tumors (especially melanoma), the remote effects of cancer in the eye as well as fundamental issues related to phototransduction.
Carol Rasmussen
Ms. Rasmussen is a Senior Instrumentation Specialist in the Department of Ophthalmology and Visual Sciences at the University of Wisconsin School of Medicine and Public Health. Laboratory studies focus on the structural correlates of glaucomatous optic neuropathy and gene therapy. She has also been Involved in the adaptation of specialized scanning laser and microscope-based ocular imaging systems for use with non-human primates.
Ted W. Reid, Ph.D.
Dr. Reid is Professor and director of laboratories in the Department of Ophthalmology and Vision Science and is a Professor of Biochemistry and Cell Biology at Texas Tech University. He has extensive experience as a biochemist and cell biologist in investigating the modulation of cell growth and wound healing processes. Recently, he has undertaken investigations concerning the structure/function relationships of neuropeptides as they relate to a variety of physiological functions.
Nader Sheibani, Ph.D.
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Dr. Sheibani is an Associate Professor in the Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health. As a molecular and cell biologist, he is interested in mechanisms that keep angiogenesis in check and how their alterations under pathological conditions, such as ischemia or diabetes, results in neovascularization. He has developed a number of in vivo (developing retinal vasculature, oxygen-induced ischemic retinopathy, diabetes) and in vitro (retinal endothelial cells, pericytes, and astrocytes proliferation, migration, and capillary formation) models to study these mechanisms. This knowledge will be instrumental in design of agonists and/or antagonists that modulate angiogenesis.
Lauren Trepanier, DVM, PhD
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Dr. Trepanier is an Associate Professor of Medicine at the University of Wisconsin School of Veterinary Medicine. She is board certified by the American College of Veterinary Internal Medicine and the American College of Veterinary Clinical Pharmacology. Her research interests are idiosyncratic drug toxicity, pharmacogenetics, and comparative drug biotransformation among species.
James N. Ver Hoeve, PhD
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Dr. Ver Hoeve is Senior Scientist in the Department of Ophthalmology and Vision Science, University of Wisconsin School of Medicine and Public Health and is Director of Electrodiagnostic Services. He is responsible for electroretinographic and visual evoked potential testing in human patients and has conducted research in numerous animal models. He is currently investigating neuroprotection strategies in a non-human primate model of experimental glaucoma.
Hugh D. Wabers, B.A.
Website
Mr. Wabers is a medical photographer with the Fundus Photograph Reading Center, Department of Ophthalmology and Visual Sciences, University of Wisconsin–Madison. He is an expert in the acquisition of fundus images and routinely conducts fluorescein angiographic studies.
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