Education

• Current- Professor of Surgery, University of Wisconsin

• DVM 1981, University of Georgia
• Internship 1982, Purdue University
• Surgical Residency 1985, University of Pennsylvania
• MS 1989, University of Wisconsin
• PhD 1994, University of Wisconsin

Research

Mechanisms of cellular injury during hypothermia and ischemia. Current focus is on the effects of bioactive peptides on kidneys stored ex vivo at low temperatures. The thrust of this work is to reduce injury to organs stored for transplantation in order to reduce the incidence of delayed function and chronic allograft nephropathy as well as to increase the donor organ supply for human transplantation. Other ongoing research projects include studies on engineering the molecular basis of wounds for augmentation of healing, studies targeted at improving the outcomes in clinical feline kidney transplantation, development of new methods for treatment of chylothorax in dogs and cats and studies on novel methods for performance of cardio-pulmonary bypass for heart surgery.

Responsibilities

Small animal general surgery, lectures, labs, and clinical instruction and research.

Clinical Interests

Organ transplantation, basic biology of wound healing, plastic  and reconstructive surgery, and treatment of chylothorax.

Recent Publications

- McAnulty, J.F. The effect of calcium on hypothermia-facilitated resuscitation of warm ischemic kidney tissue slices. A role for the mitochondrial permeability transition pore? Cryobiology 36:12-19, 1998.

- McAnulty, J.F. Hypothermic storage of feline kidneys for transplantation: Successful ex vivo storage up to 7 hours. Vet Surg 27: 312-320, 1998.

- Robinson T.M., Dubielzig R.R., McAnulty J.F.. Malignant mesenchymoma associated with an unusual vasoinvasive metastasis in a dog. J. Amer. Animal Hosp. Assoc.,  34:295-299,  1998.

- McAnulty J.F. and G.L. Lensmeyer. Comparison of high performance liquid chromatography and immunoassay methods for measurement of cyclosporine A blood levels after feline kidney transplants. Vet. Surg. 27:589-595, 1998.

- McAnulty J.F. The effect of short term hypothermic storage on viability of cancellous bone grafts. Am. J. Vet. Res. 60:63-67, 1999.

- McAnulty J.F. and Lensmeyer G.L.. The effects of ketoconazole on the pharmacokinetics of cyclosporine A in the cat. Vet. Surg. 28:448-455, 1999   

- McAnulty, J.F. and Waller, K. The effect of quinacrine on oxidative stress in kidney tissue stored at low temperature after warm ischemic injury.  Cryobiology 39:197-204, 1999.

- Bjorling D., McAnulty J., Swainson S. Surgically treatable upper respiratory disorders. Vet Clin of N Amer 30:1227-1251, 2000.

- Patricelli A.J., Hardie R.J.,  McAnulty J.F. Cyclosporine and Ketoconazole for the Treatment of Perianal Fistulas in Dogs. JAVMA 220:1009-1016, 2002.

- McAnulty J. F., Reid T.W., Waller K.R., and Murphy C.J. Successful six day kidney preservation using trophic factor supplemented media and simple cold storage. American Journal of Transplantation. 2: 712-718, 2002.

- Katayama M., McAnulty J.F.. Renal transplantation in cats: Selection and preoperative management. Compendium on Continuing Education for the Practicing Veterinarian 24:868-873, 2002.

- Katayama M., McAnulty J.F.. Renal transplantation in cats: Techniques, complications and immunosuppression. Compendium on Continuing Education for the Practicing Veterinarian 24:874-882, 2002.

- Gellasch K.L., DeCosta Gomez T., McAnulty J.F., Bjorling D.E.. Use of intraluminal nitinol stents in the treatment of tracheal collapse in a dog. JAVMA 221:1719-1723, 2002

- Gellasch K.L., Patricelli A.J., Sicard G.K., McAnulty J.F.. Use of portocaval venografts with ameroid constrictor placement and hepatic lobectomy for treatment of intralobular intrahepatic portocaval shunts in four dogs. JAVMA 222: 455-460, 2003.

- Bryant K.J., Moore K., McAnulty J.F.. Angularis Oris Axial Pattern Buccal Flap for Reconstruction of Recurrent Fistulae of the Palate. Vet Surg 32:113-119, 2003.

- Bryant K.J., Steinberg H., McAnulty J.F.. Cranioplasty by molded polymethylmethacrylate prosthesis reconstruction for radical excision of neoplasms of the skull. JAVMA 223: 67-72, 2003.

- McAnulty J.F.. Chapter 85, Pectus Excavatum. Textbook of Respiratory Disease in Dogs and Cats, Ed . Lesley King, Saunders Press, St. Louis, MO, 643-647, 2004.

- Headrick J.F., McAnulty J.F..  Reconstruction of a bilateral hypoplastic soft palate in a cat. JAAHA 40:86-90, 2004.

- Ambiru S., Uryuhara K., Talpe S., Dehoux J.P., Jacobi L, Murphy C.J., McAnulty J.F., Gianello P. Improved survival of orthotopic liver allograft in swine by addition of trophic factors to UW solution.Transplantation 77:302-319, 2004.

-McAnulty J. F., Foley, J.D., Reid T.W., Heath, T.D., Waller K.R., and Murphy C.J  Suppression of Cold Ischemic Injury in Stored Kidneys by the Antimicrobial Peptide Bactenecin. Cryobiology, 49: 230-240, 2004.

- Djamali A. Waller K.R., McAnulty J.F., Hullett D., Becker B.N., Odorico J.S. Intrathymic injection of anti-Fas monoclonal antibody prolongs murine non-vascularized cardiac allograft survival. Transpl Int. 17:301-309, 2004.

- Sicard G.K., Waller, K.R., McAnulty J.F. The Effect of Cisterna Chyli Ablation Combined with Thoracic Duct Ligation on Abdominal Lymphatic Drainage. Vet Surg, 34:64-70, 2005.

- Adams W.M., Bjorling D.E., McAnulty J.F., Green E.M., Forrest L.J., Vail D.M. Presurgical accelerated radiotherapy for canine nasal tumors. JAVMA 227: 936-941, 2005.

- Hardie R.J., Schmiedt C., Phillips L., McAnulty J.F.. Ureteral Papilla Implantation as a Technique for Neoureterocystostomy in Cats. Vet Surg, 34: 393-398, 2005.

- Hayashi K., Sicard G., Gellasch K., Frank J.D., Hardie R.J., McAnulty J.F. Cisterna chyli ablation with thoracic duct ligation for chylothorax: Results in eight dogs. Vet Surg 34:519–523, 2005.

- Schmiedt C., Penzo C., Schwab M., Dubielzig R., McAnulty J.F. Use of Capecitabine After Renal Allograft Transplantation  in DEA-Matched Dogs. Vet Surg 35:113-124, 2006.

- McAnulty J.F. Idiopathic chylothorax. Veterinary Forum Vol 23, 41-47, 71, 2006.

- Milovancev M, Schmiedt C., Bentley E., Schwab M, Dubielzig R.,  McAnulty J.F. Use of capecitabine to prevent acute renal allograft rejection in DEA-mismatched mongrel dogs.

Vet Surg 36:10-20, 2007.

- Kwon Y.S., Foley J.F., Murphy C.J., McAnulty J.F. The Effect of Trophic Factor Supplementation on Cold Ischemia-Induced Early Apoptotic Changes. Transplantation 83:91-94, 2007.

- Schmiedt C.W., Schwab M.C., Dubielzig R.R., Murphy C.J., McAnulty J.F.. Trophic Factor Supplemented UW Solution Reduces Intimal Hyperplasia in the Rat Aortic Transplant Model.  Cryobiology 54:204-211, 2007.

- Zarfoss M., Bentley E., Milovancev M., Schmiedt C., Schwab M., Dubielzig R., McAnulty J.F.  Clinical and histopathologic evidence of capecitabine corneal toxicity in dogs. Vet Pathol 44:700-702, 2007

- Murphy S.M., Rodriguez D., McAnulty J.F.. Minimally invasive cholecystostomy catheter placement for management of extrahepatic biliary obstruction in animals. Vet Surg 36: 675-683, 2007.

- Gallegos J., Schmiedt C.W., McAnulty J.F. A new method for cosmetic nasal reconstruction following nasal planum and premaxilla resection: technique and results in 2 dogs. Vet Surg 36:669-674, 2007

- Waller K.R., Foley J.D., McAnulty J.F., Murphy C.J. Trophic factor supplementation protects kidney tubule cells from cold ischemic injury and decreases free radical production during rewarming. Cell Preservation Technology 5: 132-136, 2007.

- Schmiedt C.W., Fern A. Delany F.A., McAnulty J.F.  Ultrasonographic determination of resistive index and graft size for evaluating clinical feline renal allografts: A retrospective study 

Veterinary Radiology & Ultrasound 49: 73-80, 2008.

- Nam H.S., McAnulty J.F., Seo J.B., Kwak H.H., Kim Y.T.,  Yoon B.I., Park I.C., Hyun C.B., and Woo H.M.. Microemulsified cyclosporine-induced gingival overgrowth in a canine renal transplantation model.  Vet Surg 37:247-53, 2008.

- Gallegos J., Schwarz T., McAnulty J.F. Massive midline occipito-temporal resection of the skull for treatment of multilobular osteochondrosarcoma: results in two dogs. JAVMA  233:752-7, 2008.

- Kwon Y.S., Foley J.D., Russell P., McAnulty J.F., Murphy C.J. Prevention of Cold Ischemia/Rewarming-induced ERK 1/2, p38 Kinase and HO-1 activation by Trophic Factor Supplementation of UW solution. Cryobiology 57:72-4, 2008.

-Schmiedt C.W., Holzman G., Schwartz T., McAnulty J.F Survival, complications, and analysis of risk factors after renal transplantation in cats: 62 cases Vet Surg In Press 2008