Education

• Case Western Reserve                2001-02            Postdoctoral fellow 
  University,Cleveland, OH                                   Repro & Molecular
                                                                               Endocrinology

• Case Western Reserve            2001            PhD
  University, Cleveland, OH

• University of Wisconsin School         1993        DVM (with honors)
  of Veterinary Medicine  

• University of Wisconsin,           1988        BS        Biochemistry (with honors)
  Madison, WI

Research

The Jorgensen lab uses cell and molecular biology tools to identify genes that are sexually dimorphic during sex differentiation, characterize their functional significance, and finally, understand how they are regulated.  Currently, we are focusing on two genes: steroidogenic factor 1 (Sf1) and Iroquois homeobox factor 3 (Irx3).

 Visit the JORGENSEN LAB WEBSITE for more information.

Responsibilities

Assistant Professor

• Pharmacology

Graduate Training

• Cellular and Molecular Biology
  
• Endocrinology Reproductive Biology Research Program
  
• Center for Women's Health Research
  
• Comparative biosciences program
• Molecular Biology Training Program

Recent Publications

Jorgensen JS, Gao L  2005  Irx3 Is Differentially Up-regulated in Female Gonads During Sex Determination Gene Expr Patterns  5/6:756-762 [Abstract]

Jorgensen JS, Quirk CC, Nilson JH  2004  Multiple and overlapping combinatorial codes orchestrate hormonal responsiveness and dictate cell-specific expression of the genes encoding LH.  Endocr Rev  25:521-542.  [Abstract]

Chipuk JE, Cornelius SS, Pultz NJ, Jorgensen JS, Bonham MJ, Kim SJ, Danielpour D  2002  The androgen receptor represses TGF-beta signaling through interaction with Smad3.  J Biol Chem 277(2):1240-8. [Abstract]

Jorgensen JS, Nilson JH  2001  Androgen receptor suppresses the luteinizing hormone b subunit by interacting with SF-1.  Mol Endocrinol 15(9):1505–1516. [Abstract]