Etiologic agent = Yersinia pestis
Yersinia pestis, a Gram (-), facultative anaerobe, bipolar
rod, is an organism steeped in history. It was the cause of the
Justinian Plague in the 6th century and "The Black Death"
in the Middle Ages, during which one-fourth of Europe's population
died. Another pandemic of plague killed over 12 million people
around the world from 1896-1930. But plague continues to be a
disease of importance in some regions of the world today, especially
parts of Asia, Africa and South America (Peru, Ecuador, Bolivia,
Brazil).
- In the 1980's, there were more than 8,000 cases of human
plague reported to the WHO.
In the U.S., plague foci are located throughout the western
states, especially in Colorado, New Mexico (New Mexico has accounted
for 50% of the 377 human cases in the U.S. since 1970), Arizona
and California. However, cases can appear anywhere in the U.S.
when people or animals travel from endemic to other areas. (See
the M.M.W.R. [2003] report of two people who were diagnosed with
plague in New York City after traveling from New Mexico.)
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