Research and Development

The Johne's Service Center conducts basic and applied research on Johne's disease pathogenesis and epidemiology as well as the biology of M. paratuberculosis. This work is supported in part by grants from state, federal, and private agencies. Clinical investigations, pilot studies, and research and development work on diagnostic tests are supported by revenue from the Center's diagnostic services. Studies currently in progress are:

Analysis of T-lymphocytes subsets in cattle infected with M. paratuberculosis
Analysis of the role of interferon-gamma in control of M. paratuberculosis infections
Evaluation of diagnostic tests for Johne's disease in experimentally infected cattle
Evaluation of diagnostic tests for Johne's disease in six naturally infected herds
Measurement of the thermal tolerance of M. paratuberculosis
Measurement of the effects of low pH and high salt on M. paratuberculosis survival
Demonstration project on rapid elimination of M. paratuberculosis from a dairy herd
Screening of natural products for ability to kill M. paratuberculosis in vitro
Herd investigations on Johne's disease in pygmy goats
Development of diagnostic tests for M. paratuberculosis infections in humans

For specific information contact Dr. Mike Collins:

Office telephone: 608-262-8457

FAX: 608-265-6463

Email: collinsm@svm.vetmed.wisc.edu

Last revised February 19, 1997.
URL is http://www.vetmed.wisc.edu/pbs/johnes/research.html.
Web Designer can be contacted at mcdonal7@facstaff.wisc.edu

All material Copyright © 1996 by the Board of Regents of the University of Wisconsin System. School of Veterinary Medicine, all rights reserved. If you have questions or comments about this page email us at: mcollin5@facstaff.wisc.edu