Ian Duncan’s Publications 2006-2009

QSI and DTI of excised brains of the myelin-deficient rat. Bar-Shir A, Duncan ID, Cohen Y. Neuroimage. 2009 Oct 15;48(1): 109-16.

Minocycline attenuates experimental autoimmune encephalomyelitis in rats by reducing T cells infiltration into the spinal cord. Nikodemova M, Lee J, Fabry Z, and Duncan ID. J. Neuroimmunol. 2009 219, 33-37.

His36Pro point-mutated proteolipid protein retained in the endoplasmic reticulum of oligodendrocytes in the shaking pup. Song J, Goetz BD, Duncan ID. Glia, 2006 53(3), 257-265.

Galactocerebrosidase-deficient  oligodendrocytes maintain stable central myelin by exogenous replacement of the missing enzyme in mice.Kondo Y, Wenger DA, Duncan ID. Proc. Nat. Acad. Sci., 2005, 102, 18670-18675.

Canine spongiform leukoencephalomyelopathy is associated with a missense mutation in cytochrome b. Li F-Y, Cuddon PA, Song J, Wood SL, Patterson JS, Shelton GD, Duncan ID. Neurobiol. Dis., 2006 21, 35-42.

Minocycline attenuates inhibitory effects on multiple mitogen-activated protein kinases and IкBα degradation in a stimulus-specific manner in microglia. Nikodemova M, Duncan ID, Watters JJ. J.Neurochem., 2006, 96(2), 314-323.

High b-value q-space diffusion MRI in myelin-deficient rat spinal cords. Biton IE, Duncan ID, Cohen,Y. Mag. Res. Imag., 2006, 24(2), 161-166.

Myelin water fraction in human cervical spinal cord in vivo. Wu Y, Alexander AL, Fleming JO, Duncan ID, Field AS. J. Comp. Assist. Tomog., 2006, 30, 304-306.

Minocycline down-regulates MHC II expression in microglia through inhibition of IRF-1 and PKC Nikodemova M., Watters J, Jackson S., Yang S., Duncan ID. J. Biol. Chem,2007, 282 (20), 15208-15216. 

q-Space Diffusion of Myelin-Deficient Spinal Cords. Biton IE, Duncan, ID, Cohen Y. Magnetic Resonance in Medicine. 2007 58, 993-1000.

Myelin, diffusion time and apparent diffusion anisotropy in the CNS: Time dependent q-space diffusion spectroscopy and imaging of myelin deficient rat spinal cords, Biton IE, Duncan ID, Cohen Y. Magnetic Resonance in Medicine, 2007.

Replacing cells in multiple sclerosis. Duncan ID. J. Neurol Sci., 2008 265, 89-92.

Stem cell therapy in multiple sclerosis: Promise and controversy. Duncan ID, Goldman S, Macklin WB, Rao M, Weiner LP, Reingold SC. Multiple Sclerosis Journal, 2008 14, 541-546.

Generation of cultured oligodendrocyte progenitors from rat neonatal brains. Larsen EC, Kondo Y, Fahrenholtz CD, Duncan, ID.  Curr. Protoc. Stem Cell Biol.
2008 Aug; Chapter 2:Unit 2D.1.1-2D.1.13.

Qualification of myelin and axon pathology during relapsing progressive experimental autoimmune encephalomyelitis in the Biozzi ABH mouse. Jackson, SJ, JangEun L, Nikodemova M, Fabry Z, Duncan ID. J. Neuropathol. Exp. Neurol. 2009, 68, 616-25.

Selective reduction in microglia density and function in the white matter of colony stimulating factor-1 deficient mice. Kondo Y and Duncan ID. J. Neurosci. Res. 2009, 87, 2686-95.

Extensive remyelination of the CNS leads to functional recovery. Duncan ID, Brower A, Kondo Y, Curlee Jr. J, Schultz R. Proc. Natl. Acad. Sci. 2009, 106, 6832-6.

Larsen EC and Duncan ID. Transplantation of stem cells and their derivatives in the treatment of multiple sclerosis. In: Stem Cell Biology on Health and Disease. Springer Press. Eds: Dittmar T and Zanker K. (In Press, 2009).