Introduction
Rotation Guide
Ophthalmic Exam
Ophthalmic Drugs
Glossary
Cases
Suggested Reading
VMTH Homepage
UW SVM Homepage
University of California at Davis Ophthalmology Site
Vetmed Center

COMMON OPHTHALMIC DRUGS

Dyes

Fluorescein – used to detect loss of corneal epithelium/for Seidel’s test
Rose Bengal – stains dead corneal epithelial cells (indicator of herpes keratitis)
Indocyanine Green (ICG) – used to stain lens capsule during cataract surgery

Topical Anesthetics

Proparacaine – anesthesia begins in 15 seconds, last for 15-20 minutes

Mydriatics/Cycloplegics

Mydriatics

Phenylephrine – recovery after 6 hours (10% soln.)

Cycloplegic Mydriatics (Anticholinergics)

Atropine – recovery after 7-10 days
Tropicamide – recovery after 5-6 hours

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Anti-Inflammatories

Corticosteroids

Dexamethasone – 0.1% solution or suspension (equivalent of 1% prednisolone)
Prednisolone – 0.125% and 1% solution or suspension
Triamcinolone – suspension given sub-conjunctivally – lasts for days

NSAIDS

Flurbiprofen – post-surgical inflammation/prevention of intraoperative miosis
Suprofen

Artificial Tears and Lubricants

Carboxymethylcellulose/Hydroxypropyl Methylcellulose (Celluvisc/Goniosol)
White Petrolatum/Mineral Oil/Lanolin (Puralube)

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Anti-Infectives

Antibiotics

“Small Guns” (general, broad spectrum -- prophylactic, erosions, conjunctivitis)

Neomycin – ‘Neo’ in triple antibiotic
Polymyxin B – ‘Poly’ in triple antibiotic
Bacitracin – ‘Bac’ in triple antibiotic ointment
Gramicidin – ‘Gram’in triple antibiotic drops
Gentamicin
Oyxtetracycline (Terramycin) – commonly used in feline conjunctivitis  

“Big Guns” (use usually indicated by culture – stromal loss, infected or melting ulcers)

Ciprofloxacin (Ciloxan)
Ofloxacin (Ocuflox)
Tobramycin
Cefazolin
Chloramphenicol

Antifungal

Miconazole – ointment
Itraconazole – given in DMSO

Antiviral

Trifluridine (Viroptic) – solution
Vidarabine (Vira-A) – ointment

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Glaucoma

Epinephrines – reduce IOP through increased aqueous outflow

Epinephrine
Dipivefrin (Propine) – prodrug of epinephrine

Beta Blockers – reduce the rate of aqueous production

Timolol – combined with dorzolamide in Cosopt
Betaxolol (Betoptic)

Direct Acting Miotics – reduce resistance to aqueous outflow

Pilocarpine
Carbachol (Miostat) – used intraocularly during cataract surgery

Cholinesterase Inhibitor Miotics – reduce resistance to aqueous outflow

Physostigmine
Demecarium (Humorsol)

Carbonic Anhydrase Inhibitors – reduce the rate of aqueous production

Methazolamide (Neptazane) – oral
Dorzolamide (Trusopt) – topical/combined with timolol in Cosopt
Brinzolamide (Azopt) – topical

Prostaglandins – increase aqueous outflow

Latanoprost (Xalatan)

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Hyperosmotic Agents

Topical

Hypertonic Sodium Chloride (Muro 128) – topical/temporary relief of corneal edema

Intravenous

Mannitol – reduction of IOP in acute glaucoma

Surgical Adjuncts

Intraocular Irrigation

BSS (Balanced Salt Solution)

Povidone Iodine

Betadine – 5% solution used for surgical prep

Viscoelastic Agents

Sodium Hyaluronate (Hylartin) – maintains the anterior chamber during intraocular surgery

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Please send any comments or questions to shermank@svm.vetmed.wisc.edu. Last modified on June 22, 2003 by Kim Sherman.