Welcome to the Vezina Lab

The Vezina lab uses the fetal mouse prostate as a model system to elucidate prostate growth stimulatory and inhibitory signals and investigate interactions between them in clinically relevant models of prostate disease. Our ultimate goal is to identify new pharmacological targets for prostate disease intervention. We are investigating how male hormones initiate prostate ductal formation, how prostate ducts elongate into surrounding mesenchyme, and how both of these processes are patterned in three dimensions to give rise to a bilaterally symmetrical prostate gland comprised of anterior dorsal, lateral, and ventral lobes. We test whether pharmacological agents disrupt these normal processes of prostate development and whether they will also block the abnormal processes contributing to prostate diseases in men.

University of Wisconsin | School of Veterinary Medicine | CBS homepage

Feedback, questions or accessibility issues? contact galoughr@.wisc.edu