James Windelborn,
PhD
Post-Doctoral
Trainee

Email:
jawindelborn@wisc.edu
My work focuses on cell-cell interactions and their role in neuroplasticity
following spinal cord injury. An ultimate goal of this research is
to regulate neuron-glia interactions as a means of enhancing spinal
plasticity in spared motor pathways to respiratory motor neurons following
high cervical hemisection. Three main questions are currently being
pursued:
-
Do microglia, astrocytes and/or oligodendrocytes undergo morphological
changes suggesting activation in the spinal ventral horn at
distance from the hemisection?
-
Do glial cells produce growth and trophic factors that contribute
to neuroplasticity in spared motor pathways, potentially contributing
to functional recovery?
-
Do treatments that enhance or restrain glial injury responses
enhance recovery from spinal injury?