James Windelborn, PhD
Post-Doctoral Trainee

Email: jawindelborn@wisc.edu

My work focuses on cell-cell interactions and their role in neuroplasticity following spinal cord injury. An ultimate goal of this research is to regulate neuron-glia interactions as a means of enhancing spinal plasticity in spared motor pathways to respiratory motor neurons following high cervical hemisection. Three main questions are currently being pursued:

• Do microglia, astrocytes and/or oligodendrocytes undergo morphological changes suggesting activation in the spinal ventral horn at distance from the hemisection?
  
  
• Do glial cells produce growth and trophic factors that contribute to neuroplasticity in spared motor pathways, potentially contributing to functional recovery?
  
  
• Do treatments that enhance or restrain glial injury responses enhance recovery from spinal injury?