Publications:
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1. Hornberger TA, Sukhija KB, Wang XR and Chien
S. mTOR is the rapamycin-sensitive kinase that confers mechanically-induced
phosphorylation of the hydrophobic motif site Thr(389) in p70(S6k).
FEBS Letters 2007 Oct 2; 581 ( 24 ): 4562-6.
2. Hornberger TA, Sukhija KB and Chien S. Regulation
of mTOR by Mechanically Induced Signaling Events in Skeletal Muscle.
Cell Cycle 2006 Jul 1; 5(13): 1391-1396.
3. Hornberger TA, Chu WK, Mak YW, Hsiung JW, Haung
S, and Chien S. The Role of Phospholipase D and Phosphatidic Acid in
the Mechanical Activation of mTOR Signaling in Skeletal Muscle.
Proc Natl Acad. Sci USA 2006 Mar 21;103(12): 4741-6.
4. Hornberger TA, Chien S. Mechanical Stimuli and
Nutrients Regulate Rapamycin-Sensitive Signaling Through Distinct Mechanisms
in Skeletal Muscle. J. Cell. Biochem. 2006 Apr; 97(6): 1207-1216.
5. Hornberger TA, R.D. Mateja, J.L. Andrews and K.A.
Esser. Aging does not alter the mechanosensitivity of the p38, p70S6k
and JNK2 signaling pathways in skeletal muscle. J Appl Physiol.
2005 Apr; 98(4) 1562-1566. Chosen for commentary.
6. Hornberger TA, Armstrong D, Koh, T. Burkholder
T, Esser KA. Intracellular Signaling Specificity in Response to Uniaxial
vs. Multiaxial Stretch: Implications for Mechanotransduction. Am
J Physiol Cell Physiol. 2005 Jan; 288(1): C185-C194.
7. Hornberger TA, R. Stuppard, K.E. Conley,
M.J. Fedele, M.L. Fiorotto and K.A. Esser. Mechanical Stimuli Regulate
Rapamycin-Sensitive Signaling by a Phosphoinositide 3- kinase, Protein
Kinase B and Growth Factor Independent Mechanism. Biochem J.
2004 Jun 380(Pt 3): 795-804.
8. Hornberger TA, Esser KA. Mechanotansduction and
the Regulation of Protein Synthesis in Skeletal Muscle, P. Nutr.
Soc. 2004 May; 63(2), 331-335.
9. Brodsky IG, Suzara D, Hornberger TA, Goldspink
P, Goldspink P, Yarasheski K, Smith S, Kukowski J, Bedno S. Posttranscriptional
Inhibition of Myosin Heavy Chain IIx Production by Isoenergetic Dietary
Protein Restriction in Humans. J. Nutr 2004 Feb; 134(2):328-34.
10. Hornberger TA, Farrar R. A Model of Progressive
Resistance Exercise that Produces Absolute Hypertrophy in the Rat. Can.
J. Appl. Physiol. 2004 Feb;29(1):16-31.
11. Hornberger TA, McLoughlin TJ,, Leszczynski1JK,
Bowen PE, Hwang ES, Hou H, Moustafa MA, Carlson BA, Hatfield DL, Diamond
AM and Esser KA. Enhanced exercise-induced muscle adaptation in selenoprotein-deficient
transgenic mice. J. Nutr. 2003 Oct; 133(10): 3091-3097.
12. McLoughlin TJ, Mylona E, Hornberger TA, Esser
KA, Pizza FX. Inflammatory cells in rat skeletal muscle are elevated
after electrically stimulated contractions. J. Appl. Physiol.
2003 Mar; 94(3):876-82.
13. Nader GA, Hornberger TA, Esser KA.Translational
Control: Implications for Skeletal Muscle Hypertrophy. Clin Orthop.
2002 Oct; 403, S178-S187.
14. Hornberger TA, Hunter RB, Kandarian SC, Esser
KA. Regulation of translation factors during hind limb unloading and
denervation of skeletal muscle in rats. Am J Physiol Cell Physiol
2001 Jul;281(1):C179-87.
Publications In S UBMISSION and Preparation
15. Andrews JL, McCarthy JJ, McDearmon-Blondell E,
Hornberger TA, Barber BK, Russell B, Walker J, Hogenesch J, Takahashi JS
and Esser KA. Circadian regulation of MyoD and Pgc-1 in
skeletal muscle: Implications for muscle function, metabolism and insulin
sensitivity. Current Biology, In Submission
16. Brodsky IG, Carper, M, Goldspink, P, Hornberger
TA, Suzara D, Kukowski J and Bedno S. Isoenergetic dietary protein restriction
and skeletal muscle myosin isoform composition in type 1 diabetes mellitus.
J. Nutr., In Submission
17. DiPasquale DM, Cheng M, Huang SA, Rooijen NV,
Hornberger TA and Koh TJ. Macrophages and Urokinase-Type Plasminogen
Activator ares Necessary for Skeletal Muscle Hypertrophy. J. Cell
Sci. In Submission
18. Palmisano1 MG, Shannon N. Bremner SN, Hornberger
TA, Shah SB, Kellermeyer M, Ryan AF and Lieber RL Skeletal Muscle Intermediate
Filaments Act as a Stress-Transmitting and Stress-Transducing Signaling
Network. In Prepartation
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