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Recent Publications:

O'Neil TK, Duffy LR, Frey JW, Hornberger TA. The role of phosphoinositide 3-kinase and phosphatidic acid in the regulation of mammalian target of rapamycin following eccentric contractions. J. Physiol. 2009 Jul 15;587(Pt 14):3691-701.

Frey JW, Farley EE, O'Neil TK, Burkholder TJ, Hornberger TA. Evidence that Mechanosensors with Distinct Biomechanical Properties Allow for Specificity in Mechanotransduction. Biophys J.
2009 Jul 8;97(1):347-56.

Goodman C.G., Mabrey D., Frey J.W., Lincoln H.C., Miu M.H., Schmidt E.K., Pierre P., and Hornberger T.A. Novel Insights into the Regulation of Skeletal Muscle Protein Synthesis as Revealed by a New Non-Radioactive In-Vivo Technique. FASEB J., 2010 Nov; In Press

Goodman CA, Miu MH, Frey JW, Mabrey DM, Lincoln HC, Ge Y, Chen J, Hornberger TA. A PI3K/PKB-Independent Activation of mTOR Signaling Is Sufficient to Induce Skeletal Muscle Hypertrophy. Mol Biol Cell. 2010 Sep;21(18):3258-68.

Goodman CA, Mayhew DL, and Hornberger TA. Recent Progress Towards Understanding the Molecular Mechanisms that Regulate Skeletal Muscle Mass. Cell Signal., 2011 Dec;23(12):1896-906.

Hornberger TA. Mechanotransduction and the Regulation of mTORC1 Signaling in Skeletal Muscle. Int. J. Biochem. Cell Biol. 2011 Sep;43(9):1267-76.

Goodman CA, Frey JW, Mabrey DM, Jacobs BL, Lincoln HC, You JS, and Hornberger TA. The Role of Skeletal Muscle mTOR in the Regulation of Mechanical Load-Induced Growth. J. Physiol, 2011 Nov 15;589(Pt 22):5485-501.

Goodman CA, Pierre P, and Hornberger TA. Imaging of Protein Synthesis with Puromycin. Proc Natl Acad. Sci USA, 2012 Apr 24;109(17):E989.

Goodman CA, Kotecki JA, Jacobs BL, and Hornberger TA. Muscle Fiber Type-Dependent Differences in the Regulation of Protein Synthesis. PLoS One, 2012 May 22;7(5):e37890.

You JS, Frey JW, and Hornberger TA. Mechanical Stimulation and Phosphatidic Acid Induce mTOR Signaling via an ERK-independent Mechanism. PLoS One, 2012 Oct 15:7(10): e47258.

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